Kamppeter B, Degenring R F, Jonas J B
Universitätsaugenklinik Mannheim, Fakultät für Klinische Medizin, Ruprechts-Karls-Universität Heidelberg, Mannheim.
Ophthalmologe. 2003 Dec;100(12):1085-90. doi: 10.1007/s00347-003-0893-0.
A photo-stress test was conducted at the subjective contrast threshold to evaluate whether psychophysical differences could be detected between chronic open-angle glaucoma patients and normal subjects.
The prospective, comparative, clinical observational study included 20 patients (29 eyes) with chronic open-angle glaucoma and 20 control subjects (29 eyes). The study groups did not vary significantly in age and refractive error, but visual acuity showed a difference of 0.16. All participants underwent photo-stress using the Kontrastometer BA4.
In the glaucoma group compared with the control group, the mean contrast threshold was significantly higher and the readaptation time significantly longer. The latter correlated significantly with the papillo-morphological glaucoma stage.
In patients with chronic open-angle glaucoma, the foveal recovery time after a photo-stress test is significantly prolonged compared with normal subjects. It may suggest involvement of the fovea in glaucoma even if the visual acuity is 20/20.
在主观对比度阈值下进行光应激试验,以评估慢性开角型青光眼患者与正常受试者之间是否能检测到心理物理学差异。
这项前瞻性、比较性临床观察研究纳入了20例慢性开角型青光眼患者(29只眼)和20名对照受试者(29只眼)。研究组在年龄和屈光不正方面无显著差异,但视力相差0.16。所有参与者均使用Kontrastometer BA4进行光应激试验。
与对照组相比,青光眼组的平均对比度阈值显著更高,重新适应时间显著更长。后者与青光眼乳头形态学分期显著相关。
与正常受试者相比,慢性开角型青光眼患者在光应激试验后的中央凹恢复时间显著延长。这可能提示即使视力为20/20,中央凹也参与了青光眼的发病过程。