Sewards Terence V
Sandia Research Center, 21 Perdiz Canyon Road, Placitas, NM 87043, USA.
Brain Res Bull. 2004 Jan 15;62(4):271-83. doi: 10.1016/j.brainresbull.2003.10.004.
It is proposed that in the gustatory system there exist separate sensory and hedonic (reward-aversion) representations in each of the primary structures in which processing of gustatory stimuli occurs. Anatomical and physiological data are used to determine putative separate sensory and hedonic representations in the nucleus of the solitary tract, parabrachial complex, gustatory thalamus, and cortical gustatory areas. In the nucleus of the solitary tract, the sensory representation is located in the rostralmost part of the nucleus, and the hedonic representation most probably in the intermediate parts. In the parabrachial complex, the sensory representation is located in the central medial and ventral lateral subnuclei, and in the waist area, and the hedonic representation in the inner division of the external lateral subnucleus and in the external medial subnucleus. In the rodent gustatory thalamic relay, the sensory representation occurs in the dorsal lateral parts of the nucleus, and the hedonic representation in the ventromedial parts. In rodent gustatory insular cortex, the sensory representation is found in anterior parts of the gustatory area, and the hedonic representation caudal to the sensory representation. The function of the separate sensory and hedonic representations is discussed in relation to the conditioned taste aversion paradigm.
有人提出，在味觉系统中，在每个发生味觉刺激处理的主要结构中都存在独立的感觉和享乐（奖赏-厌恶）表征。利用解剖学和生理学数据来确定孤束核、臂旁复合体、味觉丘脑和皮质味觉区中假定的独立感觉和享乐表征。在孤束核中，感觉表征位于核的最前端部分，享乐表征很可能位于中间部分。在臂旁复合体中，感觉表征位于中央内侧和腹外侧亚核以及腰部区域，享乐表征位于外侧亚核内侧部和内侧亚核。在啮齿动物的味觉丘脑中继中，感觉表征出现在核的背外侧部分，享乐表征出现在腹内侧部分。在啮齿动物的味觉岛叶皮质中，感觉表征位于味觉区的前部，享乐表征位于感觉表征的尾侧。结合条件性味觉厌恶范式讨论了独立感觉和享乐表征的功能。
