后代中母体呼吸道合胞病毒抗体的变化情况。
The progression of maternal RSV antibodies in the offspring.
作者信息
Hacimustafaoglu M, Celebi S, Aynaci E, Sinirtas M, Koksal N, Kucukerdogan A, Ercan I, Goral G, Ildirim I
机构信息
Uludag University Medical Faculty, Department of Pediatrics and Pediatric Infectious Diseases, Görükle, Bursa, Turkey.
出版信息
Arch Dis Child. 2004 Jan;89(1):52-3. doi: 10.1136/adc.2002.017780.
Abstract
The concentrations of maternal anti-RSV IgG antibodies were followed in 49 healthy newborns over the first six months of life. At birth, 41 mothers (83%) tested positive for anti-RSV IgG and all of their babies carried maternal anti-RSV IgG. Anti-RSV IgG positivity dropped to 73% at 1 month, 6% at 3 months, and 2% at 6 months. Between 3 and 6 months, 8% did acquire RSV infection, half of them as acute bronchiolitis and half as non-specific respiratory infection. All of the patients who acquired clinical RSV disease had an antibody concentration of <20 RU/ml which may be the cut off value for protection.
摘要
对49名健康新生儿在出生后的前六个月跟踪检测其母亲抗呼吸道合胞病毒（RSV）IgG抗体的浓度。出生时，41名母亲（83%）的抗RSV IgG检测呈阳性，她们所有的婴儿都携带母体抗RSV IgG。抗RSV IgG阳性率在1个月时降至73%，3个月时降至6%，6个月时降至2%。在3至6个月之间，8%的婴儿确实感染了RSV，其中一半为急性细支气管炎，一半为非特异性呼吸道感染。所有出现临床RSV疾病的患者抗体浓度均<20 RU/ml，这可能是具有保护作用的临界值。
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