Salom Emery M, Schey Dana, Peñalver Manuel, Gómez-Marín Orlando, Lambrou Nicholas, Almeida Zoyla, Mendez Luis
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, School of Medicine, University of Miami/Jackson Memorial Hospital, 1611 NW 12th Avenue, Holtz Building East Tower Room 3003, Miami, FL 33136, USA.
Am J Obstet Gynecol. 2003 Dec;189(6):1563-7; discussion 1567-8. doi: 10.1016/s0002-9378(03)00936-0.
The purpose of this study was to assess the complication rates of incidental appendectomies in women who undergo benign gynecologic procedures.
This was a retrospective case-controlled study of patients who did (n=100 women) or did not (n=100 women) undergo incidental appendectomies at the time of an abdominal hysterectomy between June 1995 and January 2001. Information was abstracted from hospital and clinic records and a gynecologic oncology database. Data were obtained about age, body mass index, hypertension, diabetes mellitus, the number of days with nothing by mouth, the length of hospital stay, and postoperative complications (cellulitis, fever, ileus, pneumonia, thromboembolic disease). Data were analyzed with the use of two-sample t tests, Wilcoxon Rank sum tests, chi(2) tests, and multiple logistic regressions.
There was no difference in preoperative diagnosis or operative procedure for either group. The number of patients in the group that did have incidental appendectomy versus the group that did not have incidental appendectomy with additional procedures at the time of abdominal hysterectomy was bilateral salpingo-oophorectomy (66 vs 61 women), unilateral oophorectomy (19 vs 19 women), lysis of adhesions (9 vs 8 women), and others (12 vs 8 women). Compared with the group that did not have incidental appendectomy, the group that did have incidental appendectomy was younger (mean age+/-SD: 44+/-9.6 years vs 48+/-13.6 years, P=.02) and had a lower mean body mass index (26.1+/-6.0 kg/m(2) vs 29.8+/-8.9 kg/m(2), P=.0009). No significant differences were found between the two groups (the group that did have incidental appendectomy vs the group that did not have incidental appendectomy, respectively) with respect to the following postoperative complications: fever (40 vs 27 women), cellulitis (1 vs 2 women), wound collection (4 vs 6 women), wound dehiscence (1 vs 5 women), wound abscess (7 vs 6 women), ileus (3 vs 2 women), and urinary tract infection (4 vs 10 women). The mean length of hospital stay was significantly longer in the group that did have incidental appendectomy than in the group that did not have incidental appendectomy (3.6+/-1.52 days vs 3.1+/-1.1 days, P=.006). However, the difference was no longer significant when patients who were fed electively on the postoperative day 2 were excluded from the analysis (3.16+/-1.13 days vs 3.04+/-1.13 days, P=.507). Thirty-one percent of the histologic specimens were abnormal, with fibrous obliteration being most common, and there was one case of acute appendicitis.
An incidental appendectomy at the time of benign gynecologic procedures does not increase postoperative complication rates or length of hospital stay. The inclusion of incidental appendectomies in all abdominal hysterectomies could potentially decrease the morbidity and mortality rates because of appendicitis in elderly women.
本研究旨在评估接受良性妇科手术的女性中 incidental appendectomies 的并发症发生率。
这是一项回顾性病例对照研究,研究对象为 1995 年 6 月至 2001 年 1 月期间在腹式子宫切除术中接受(n = 100 名女性)或未接受(n = 100 名女性)incidental appendectomies 的患者。信息从医院和诊所记录以及妇科肿瘤数据库中提取。获取了关于年龄、体重指数、高血压、糖尿病、禁食天数、住院时间和术后并发症(蜂窝织炎、发热、肠梗阻、肺炎、血栓栓塞性疾病)的数据。使用两样本 t 检验、Wilcoxon 秩和检验、卡方检验和多元逻辑回归分析数据。
两组的术前诊断或手术操作无差异。在腹式子宫切除术时接受 incidental appendectomy 的组与未接受 incidental appendectomy 且进行了其他手术的组相比,额外进行的手术有双侧输卵管卵巢切除术(66 名女性对 61 名女性)、单侧卵巢切除术(19 名女性对 19 名女性)、粘连松解术(9 名女性对 8 名女性)以及其他手术(12 名女性对 8 名女性)。与未接受 incidental appendectomy 的组相比,接受 incidental appendectomy 的组更年轻(平均年龄±标准差:44±9.6 岁对 48±13.6 岁,P = 0.02)且平均体重指数更低(26.1±6.0 kg/m²对 29.8±8.9 kg/m²,P = 0.0009)。两组(分别为接受 incidental appendectomy 的组和未接受 incidental appendectomy 的组)在以下术后并发症方面未发现显著差异:发热(40 名女性对 27 名女性)、蜂窝织炎(1 名女性对 2 名女性)、伤口积液(4 名女性对 6 名女性)、伤口裂开(1 名女性对 5 名女性)、伤口脓肿(7 名女性对 6 名女性)、肠梗阻(3 名女性对 2 名女性)以及尿路感染(4 名女性对 10 名女性)。接受 incidental appendectomy 的组的平均住院时间显著长于未接受 incidental appendectomy 的组(3.6±1.52 天对 3.1±1.1 天,P = 0.006)。然而,当排除术后第 2 天选择性进食的患者后进行分析时,差异不再显著(3.16±1.13 天对 3.04±1.13 天,P = 0.507)。31%的组织学标本异常,其中纤维性闭塞最为常见,且有 1 例急性阑尾炎。
在良性妇科手术时进行 incidental appendectomy 不会增加术后并发症发生率或住院时间。在所有腹式子宫切除术中纳入 incidental appendectomy 可能会降低老年女性因阑尾炎导致的发病率和死亡率。