Li Cairu, Samsioe Göran, Borgfeldt Christer, Lidfeldt Jonas, Agardh Carl David, Nerbrand Christina
Department of Obstetrics and Gynecology, Lund University Hospital, Lund, Sweden.
Am J Obstet Gynecol. 2003 Dec;189(6):1646-53. doi: 10.1016/s0002-9378(03)00872-x.
The purpose of this study was to analyze the influence of sociodemographic characteristics and environmental factors on self-reported menopause-related symptoms among middle-aged Swedish women.
Women who were born in the years 1935 to 1945 and who were living in the Lund area of southern Sweden were investigated. Each woman completed a generic questionnaire and underwent a personal interview that pertained to sociodemographic characteristics, lifestyle, and current health-related problems. With these background factors, the frequency and intensity of hot flushes and vaginal dryness were determined; risk factor analysis was evaluated with the use of the multiple regression models.
There were 6917 participants, with a response rate of 64%. A lower risk for hot flushes was related to older age, high education, and vigorous physical exercise. The major risk factors for vasomotor complaints were current weight gain, part-time employment, oophorectomy, unhealthy lifestyle, and concomitant health problems. Light smoking, late age of menopause, higher education, and excessive weight reduced the risk of vaginal dryness. However, older age, marriage, and chronic diseases negatively affected vaginal complaints. The background factors had less impact on symptoms in women who used hormone replacement therapy.
Sociodemographic characteristics, lifestyle, and concomitant health problems appear to be important modifiable determinants for menopause-related symptoms.
本研究旨在分析社会人口统计学特征和环境因素对瑞典中年女性自我报告的绝经相关症状的影响。
对1935年至1945年出生且居住在瑞典南部隆德地区的女性进行调查。每位女性完成一份通用问卷,并接受一次关于社会人口统计学特征、生活方式和当前健康相关问题的个人访谈。基于这些背景因素,确定潮热和阴道干燥的频率及强度;使用多元回归模型评估风险因素分析。
共有6917名参与者,应答率为64%。潮热风险较低与年龄较大、高学历和剧烈体育锻炼有关。血管舒缩症状的主要风险因素是当前体重增加、兼职工作、卵巢切除术、不健康的生活方式和伴随的健康问题。轻度吸烟、绝经年龄较晚、高学历和超重降低了阴道干燥的风险。然而,年龄较大、已婚和患有慢性病对阴道症状有负面影响。背景因素对使用激素替代疗法的女性的症状影响较小。
社会人口统计学特征、生活方式和伴随的健康问题似乎是绝经相关症状重要的可改变决定因素。