Saccomani Sylvio, Lui-Filho Jeffrey Frederico, Juliato Cassia Raquel, Gabiatti Jose Roberto, Pedro Adriana Orcesi, Costa-Paiva Lucia
Department of Obstetrics and Gynecology, Faculty of Medical Science, State University of Campinas, São Paulo, Brazil.
Menopause. 2017 Sep;24(9):1065-1070. doi: 10.1097/GME.0000000000000884.
To evaluate the association between vasomotor symptoms and obesity in climacteric women.
We conducted a cross-sectional population-based study of 749 women aged 45 to 60 years. The dependent variable was intensity of menopausal symptoms evaluated by the menopause rating scale questionnaire. Independent variables were sociodemographic and clinical characteristics, and obesity evaluated by body mass index.
There was no significant difference in the majority of clinical and sociodemographic characteristics between the body mass index groups. Obese women had less physical activity (P = 0.019) and a higher prevalence of hypertension (P < 0.001), diabetes (P = 0.002), urinary incontinence (P < 0.001), and urge incontinence (P = 0.0006). The total mean menopause rating scale score was 9.7. Scores for hot flashes increased progressively and were higher for participants with body mass index greater than 30 kg/m (P = 0.027). Joint and muscle pain scores also increased with increased body mass index (P < 0.001). Regarding urogenital symptoms, there was a significant difference in urinary problems only, which were more intense in obese women (body mass index >30 kg/m) (P < 0.0001). There was no significant difference in any psychological symptoms on the menopause rating scale. Factors associated with hot flash scores were higher body mass index, presence of urinary urgency, and vaginal dryness.
We found that menopausal symptoms, including vasomotor, joint, and urinary symptoms, were related to obesity. Hot flashes were associated with higher body mass index, urinary urgency, and vaginal dryness. Understanding this relationship may contribute to the development of healthcare strategies aimed at minimizing the impact of obesity on several health issues of climacteric women.
评估更年期女性血管舒缩症状与肥胖之间的关联。
我们对749名年龄在45至60岁之间的女性进行了一项基于人群的横断面研究。因变量是通过更年期评定量表问卷评估的更年期症状强度。自变量是社会人口统计学和临床特征,以及通过体重指数评估的肥胖情况。
体重指数组之间在大多数临床和社会人口统计学特征上没有显著差异。肥胖女性的身体活动较少(P = 0.019),高血压(P < 0.001)、糖尿病(P = 0.002)、尿失禁(P < 0.001)和急迫性尿失禁(P = 0.0006)的患病率较高。更年期评定量表的总平均得分是9.7。潮热得分逐渐增加,体重指数大于30kg/m²的参与者得分更高(P = 0.027)。关节和肌肉疼痛得分也随着体重指数的增加而增加(P < 0.001)。关于泌尿生殖系统症状,仅在泌尿问题上存在显著差异,肥胖女性(体重指数>30kg/m²)的症状更严重(P < 0.0001)。更年期评定量表上的任何心理症状均无显著差异。与潮热得分相关的因素是较高的体重指数、尿急和阴道干燥。
我们发现更年期症状,包括血管舒缩、关节和泌尿症状,与肥胖有关。潮热与较高的体重指数、尿急和阴道干燥有关。了解这种关系可能有助于制定医疗保健策略,以尽量减少肥胖对更年期女性多种健康问题的影响。