Sartorio A, Proietti M, Marinone P G, Agosti F, Adorni F, Lafortuna C L
Divisione Malattie Metaboliche, Istituto Auxologico Italiano, IRCCS, Piancavallo (VB), Italy.
Int J Obes Relat Metab Disord. 2004 Jan;28(1):91-8. doi: 10.1038/sj.ijo.0802433.
To depict the general trends of muscle anaerobic performance in obese subjects within a wide range of age and body weight.
Cross-sectional study for the measurement of lower limb maximal anaerobic power output with a modification of the Margaria stair climbing test in a large population of obese subjects of both genders within a wide span of age (18-80 y) and body mass index (BMI, 30-68 kg m(-2)). Furthermore, body composition was also determined by bioimpedance analysis in a representative subgroup, in order to evaluate the relationships between fat-free mass (FFM) and power output.
A total of 1298 obese subjects (486 males, 812 females) from an Italian population seeking medical support for body weight reduction. Within this sample, a consistent subgroup of 193 subjects (59 males, 134 females) was also selected for accessory study of body composition.
In general, male subjects developed significantly higher lower limb power output (W) than female subjects (P<0.001-0.01), both in absolute terms and per unit body mass. In both genders, W was influenced negatively by age (P<0.001) and positively by BMI (P<0.001). While the effect of age was similar in both genders, BMI had a different positive effect in male and in female subjects, being more definite in male subjects. In the subgroup, FFM was found to depend both on age and BMI, in a fashion comparable with that displayed by W. The gender-related differences in W disappeared when expressed per unit FFM and a significant linear correlation was found between FFM and W, both in male and female subjects (R2=0.32-0.51, P<0.001).
The lower limb maximal power output is significantly higher in obese male subjects than in female subjects, being negatively influenced by age but positively related to BMI. Female subjects appear to be at a greater disadvantage for effect of obesity, the major motor limitations being suffered by older women with higher BMI. These gender differences in age- and BMI-dependent W changes seem to be related to changes in FFM in the subgroup in whom body composition was studied.
描绘广泛年龄和体重范围内肥胖受试者肌肉无氧运动能力的总体趋势。
一项横断面研究，通过改良的马加里亚爬楼梯试验测量大量不同年龄（18 - 80岁）和体重指数（BMI，30 - 68 kg/m²）的肥胖男女受试者的下肢最大无氧功率输出。此外，还通过生物电阻抗分析在一个代表性亚组中测定身体成分，以评估去脂体重（FFM）与功率输出之间的关系。
来自意大利寻求体重减轻医疗支持的1298名肥胖受试者（486名男性，812名女性）。在这个样本中，还选取了193名受试者（59名男性，134名女性）的一个一致亚组进行身体成分的辅助研究。
总体而言，男性受试者的下肢功率输出（W）在绝对值和单位体重方面均显著高于女性受试者（P < 0.001 - 0.01）。在男女两性中，W均受到年龄的负面影响（P < 0.001）和BMI的正面影响（P < 0.001）。虽然年龄对两性的影响相似，但BMI对男性和女性受试者有不同的积极影响，在男性受试者中更为明显。在亚组中，发现FFM既取决于年龄也取决于BMI，其方式与W所显示的相似。当按单位FFM表示时，W的性别相关差异消失，并且在男性和女性受试者中均发现FFM与W之间存在显著的线性相关性（R² = 0.32 - 0.51，P < 0.001）。
肥胖男性受试者的下肢最大功率输出显著高于女性受试者，受年龄负面影响但与BMI呈正相关。女性受试者似乎在肥胖影响方面处于更大劣势，主要运动限制由BMI较高的老年女性承受。这些年龄和BMI依赖性W变化的性别差异似乎与研究身体成分的亚组中FFM的变化有关。
