Shields Carol L, Shields Jerry A
Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Surv Ophthalmol. 2004 Jan-Feb;49(1):3-24. doi: 10.1016/j.survophthal.2003.10.008.
Tumors of the conjunctiva and cornea comprise a large and varied spectrum of conditions. These tumors are grouped into two major categories of congenital and acquired lesions. The acquired lesions are further subdivided based on origin of the mass into surface epithelial, melanocytic, vascular, fibrous, neural, histiocytic, myxoid, myogenic, lipomatous, lymphoid, leukemic, metastatic and secondary tumors. Melanocytic lesions include nevus, racial melanosis, primary acquired melanosis, melanoma, and other ocular surface conditions like ocular melanocytosis and secondary pigmentary deposition. The most frequent nonmelanocytic neoplastic lesions include squamous cell carcinoma and lymphoma, both of which have typical features appreciated on clinical examination. The caruncle displays a slightly different array of tumors compared to those elsewhere on the conjunctiva, as nevus and papilloma are most common, but oncocytoma and sebaceous gland hyperplasia, adenoma, and carcinoma can be found. In this report, we provide clinical description and illustration of the many conjunctival and corneal tumors and we discuss tumor management.
结膜和角膜肿瘤包含大量不同的病症。这些肿瘤分为先天性和后天性病变两大类。后天性病变根据肿物的起源进一步细分为表面上皮性、黑素细胞性、血管性、纤维性、神经性、组织细胞性、黏液样、肌源性、脂肪性、淋巴样、白血病性、转移性和继发性肿瘤。黑素细胞性病变包括痣、种族性黑变病、原发性后天性黑变病、黑色素瘤以及其他眼表病症，如眼黑变病和继发性色素沉着。最常见的非黑素细胞性肿瘤性病变包括鳞状细胞癌和淋巴瘤，二者在临床检查中均有典型特征。与结膜其他部位相比，泪阜的肿瘤种类略有不同，痣和乳头状瘤最为常见，但也可发现嗜酸细胞瘤、皮脂腺增生、腺瘤和癌。在本报告中，我们提供了许多结膜和角膜肿瘤的临床描述及图示，并讨论了肿瘤的处理方法。
