García C, Ugalde E, Campo A B, Miñambres E, Kovács N
Department of Microbiology, Hospital Universitario "Marqués de Valdecilla", Avenida Valdecilla s/n, 39008 Santander, Spain.
Eur J Clin Microbiol Infect Dis. 2004 Feb;23(2):116-8. doi: 10.1007/s10096-003-1071-7. Epub 2004 Jan 8.
Reported here is a rare case of atypical pneumonia due to a non- pneumophila Legionella sp. that occurred in a young patient with systemic lupus erythematosus. In spite of aggressive treatment, the patient died 24 h following admission to the intensive care unit. Legionella longbeachae was cultured from respiratory tract specimens and identified to the genus level by PCR and to the species level by an immunofluorescence test. Since most current laboratory tests for Legionella spp., including urinary antigen and serology, cannot detect infections caused by non- pneumophila Legionella spp., culture on legionella-selective media should be strongly considered when diagnosing immunosuppressed patients with pneumonia.
本文报道了一例罕见的非嗜肺军团菌引起的非典型肺炎病例,该病例发生在一名患有系统性红斑狼疮的年轻患者身上。尽管进行了积极治疗,但患者在入住重症监护病房24小时后死亡。从呼吸道标本中培养出长滩军团菌,并通过PCR鉴定到属水平,通过免疫荧光试验鉴定到种水平。由于目前大多数针对军团菌属的实验室检测,包括尿抗原检测和血清学检测,都无法检测到非嗜肺军团菌属引起的感染,因此在诊断免疫抑制患者的肺炎时,应强烈考虑在军团菌选择性培养基上进行培养。