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[不同发病率地区人群中乙型肝炎和丁型肝炎病毒标志物的流行情况]

[The prevalence of the markers of viral hepatitis B and delta among the population in regions differing in the level of morbidity].

作者信息

Iashina T L, Favorov M O, Shakhgil'dian I V, Firsova S N, Eraliev A E, Zhukova L D, Reznichenko R G

出版信息

Vopr Virusol. 1992 Jul-Aug;37(4):194-6.

PMID:1471341
Abstract

From two regions differing by the levels of incidence of hepatitis B, 2019 blood serum specimens from normal population were examined for markers of HBV infection. In Moscow, among 1040 samples examined HBsAg was found in 2.0%, anti-HBs in 10.0%, anti-HBc in the absence of HBsAg and anti-HBs in 4.5%. In the Osh Province of Kirgizstan, among 979 subjects examined the same markers were found in 10.3%, 22.4%, and 14.0%, respectively. In this area, HBsAg was detected most frequently among infants (14.9% in infants under 1 year), in whom HBs-antigenemia was combined with the presence of HBeAg in 54.5% and with anti-HBc-IgM in 69.2%. Antibody to delta antigen (anti-delta) was found in 24 (25.8%) out of 93 HBsAg-positive subjects in the Osh Province but in none of 21 subjects with HBs-antigenemia in Moscow.

摘要

从两个乙肝发病率不同的地区,采集了2019份正常人群的血清样本检测乙肝病毒(HBV)感染标志物。在莫斯科,检测的1040份样本中,HBsAg阳性率为2.0%,抗-HBs阳性率为10.0%,HBsAg和抗-HBs均阴性时抗-HBc阳性率为4.5%。在吉尔吉斯斯坦奥什省,检测的979名受试者中,相同标志物的阳性率分别为10.3%、22.4%和14.0%。在该地区,婴儿中HBsAg检出率最高(1岁以下婴儿为14.9%),其中54.5%的婴儿HBs抗原血症合并HBeAg阳性,69.2%合并抗-HBc-IgM阳性。奥什省93例HBsAg阳性受试者中有24例(25.8%)检测到抗δ抗原抗体(抗-HD),而莫斯科21例HBs抗原血症受试者中均未检测到。

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