Ellen Jonathan M
Division of General Pediatrics and Adolescent Medicine, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, USA.
J Urban Health. 2003 Dec;80(4 Suppl 3):iii40-9. doi: 10.1093/jurban/jtg081.
Given the increasing numbers of new HIV infections among adolescent females and limitations of the current generation of HIV interventions, a new generation of interventions is needed to prevent HIV and other infections in this population. Interventions available today are limited by their focus on single behaviors that have little epidemiologic significance, such as condom use, and their failure to be tested among the highest risk females. Recent advances in epidemiologic sciences suggest that the next generation of interventions should focus on parenting and parenting skills, sexual risk networks in which drug use and other high-risk behaviors are prevalent, and neighborhoods where these networks exist. Future research should include formative and observational studies to inform new intervention trials that reach the highest risk female youth.
鉴于青春期女性中新发艾滋病毒感染人数不断增加，以及当前一代艾滋病毒干预措施存在局限性，需要新一代的干预措施来预防该人群中的艾滋病毒和其他感染。当前可用的干预措施存在局限性，它们侧重于单一行为，如使用避孕套，而这些行为在流行病学上意义不大，并且未能在风险最高的女性中进行测试。流行病学科学的最新进展表明，下一代干预措施应侧重于育儿和育儿技能、存在吸毒和其他高风险行为的性风险网络，以及这些网络所在的社区。未来的研究应包括形成性研究和观察性研究，以为针对风险最高的年轻女性的新干预试验提供信息。
