Funakoshi Yasunobu, Sawabata Noriyoshi, Takeda Shin-ichi, Hayakawa Masanobu, Okumura Yoshitomo, Maeda Hajime
Division of Surgery, Toneyama National Hospital, 5-1-1 Toneyama, Toyonaka, Osaka 560-8552, Japan.
Surg Today. 2004;34(1):55-7. doi: 10.1007/s00595-003-2627-y.
We report a case of pulmonary benign metastasizing leiomyoma (BML) from the uterus in a 77-year-old woman. The patient presented for investigation of multiple pulmonary nodules on a routine chest roentgenogram. Because a preoperative diagnosis could not be made, the largest tumor, 3.5 cm in diameter, was resected from the right lower lobe, and histological examination confirmed BML. She had undergone hysterectomy with oophorectomy for uterine leiomyomas 12 years earlier, at the age of 65. The microscopic findings of the lung tumor were similar to those of the uterine leiomyoma, and both lesions were histologically benign. Although this disease is considered to be hormone-dependent, metastasis was found in this elderly postmenopausal woman whose tumor was negative for estrogen receptor.
我们报告了一例77岁女性子宫来源的肺良性转移性平滑肌瘤(BML)。患者因常规胸部X线检查发现多个肺结节前来就诊。由于术前无法做出诊断,遂从右下叶切除了最大的肿瘤,直径为3.5 cm,组织学检查确诊为BML。她在12年前,即65岁时因子宫平滑肌瘤接受了子宫切除术和卵巢切除术。肺肿瘤的显微镜检查结果与子宫平滑肌瘤相似,且两个病变在组织学上均为良性。尽管该疾病被认为与激素有关,但在这位老年绝经后女性中发现了转移,其肿瘤雌激素受体为阴性。