Usui Yukio, Matsuzaki Shouji, Matsushita Kazuo, Shima Masanori
Department of Urology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Tokai J Exp Clin Med. 2003 Jul;28(2):81-7.
We intended to find risk factors for urolitiasis and its recurrence in a geriatric population.
The medical records of 209 elderly stone patients over age 65 were reviewed. They had been regularly seen at our stone clinic for a mean follow-up period of 1385 +/- 1324 days after urolithiasis was diagnosed.
The elderly population comprised 9.6 % of all the stone patients followed at the stone clinic. Regarding stone compositions, calcium oxalate and calcium phosphate were most common in the elderly patients (80 %). The incidence of uric acid stones was higher in the elderly patient group than in the younger group (10.7 % vs. 5.1 %; p = 0.0046). Recurrent stones were seen in 18 of the 207 geriatric patients (15.4 %) during the follow-up period. The urinary calcium excretion of the recurrent stone patients was significantly higher than in those without recurrence (293 +/- 138 mg vs. 177 +/- 98 mg/day, p = 0.0035). However, the probability of stone recurrence estimated by Kaplan-Meier curves was as equivalent in the elderly patient group as in the younger group.
Hypercalciuria may also play a part in stone recurrence of geriatric patients.
我们旨在找出老年人群尿路结石及其复发的危险因素。
回顾了209例65岁以上老年结石患者的病历。他们在我们的结石门诊定期就诊,尿路结石诊断后平均随访期为1385±1324天。
老年人群占结石门诊随访的所有结石患者的9.6%。关于结石成分,草酸钙和磷酸钙在老年患者中最为常见(80%)。老年患者组尿酸结石的发病率高于年轻组(10.7%对5.1%;p = 0.0046)。在随访期间,207例老年患者中有18例(15.4%)出现复发性结石。复发性结石患者的尿钙排泄量显著高于无复发患者(293±138mg对177±98mg/天,p = 0.0035)。然而,通过Kaplan-Meier曲线估计的结石复发概率在老年患者组和年轻组中相当。
高钙尿症可能也在老年患者结石复发中起作用。