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[红外光谱法与尿石症。80例报告]

[Infrared spectrometry and urolithiasis. Report of 80 cases].

作者信息

Bennani S, Debbagh A, Oussama A, el Mrini M, Benjelloun S

机构信息

Service d'urologie, CHU Ibn Rochd, Casablanca, Maroc.

出版信息

Ann Urol (Paris). 2000 Dec;34(6):376-83.

PMID:11147079
Abstract

Urolithiasis is a frequent disorder that is characterized by its recurrence following treatment and which can affect between 3-20% of the population, with an incidence that differs from country to country. The aim of the present study was to determine the composition of the calculi, and the remain characteristics of this pathology in Morocco. A series of 80 calculi was therefore analyzed by Fourier transform infrared spectroscopy. The findings showed that calcium monohydrate oxalate was the main lithiasic component, indicating that hyperoxaluria plays a major role in the formation of the calculi. The component identified were as follows: calcium oxalate (58.75%), calcium phosphate and magnesium phosphate (17.5%), uric acid (15%), and urate (8.75%). In 91.25% of cases, the calculi were of mixed composition. Regular patient follow-up is advocated and subjects should be informed of the risk factor involved, as urolithiasic recurrence was observed in 10% of the cases in this series.

摘要

尿石症是一种常见疾病,其特征是治疗后易复发,发病率在3%至20%之间,且因国家而异。本研究的目的是确定摩洛哥结石的成分以及这种病理状况的其他特征。因此,采用傅里叶变换红外光谱法对一系列80颗结石进行了分析。研究结果表明,一水合草酸钙是主要的结石成分,这表明高草酸尿症在结石形成中起主要作用。鉴定出的成分如下:草酸钙(58.75%)、磷酸钙和磷酸镁(17.5%)、尿酸(15%)和尿酸盐(8.75%)。在91.25%的病例中,结石为混合成分。提倡对患者进行定期随访,并应告知受试者所涉及的风险因素,因为在该系列病例中有10%观察到尿石症复发。

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