Melikiants A G, Malenkov A G
Biofizika. 1977 Jan-Feb;22(1):86-9.
It was found that kinetic features of the behaviour of osmotic potential differences through epithelial cells layer were characteristic of determination of mechanic properties of separate structures of intercellular junctions. The quantitative estimation of the contribution of tight junction and simple junctions to the value of mechanic connection was performed. The mechanism of structure reorganisation in intercellular junctions under osmotic pressure are discussed. A model of intercellular junctions that accounts for the essential feature of transepithelial potential differences behavior under the osmotic pressure is proposed.
研究发现,通过上皮细胞层的渗透势差行为的动力学特征是确定细胞间连接各结构力学性质的特征。对紧密连接和简单连接对力学连接值的贡献进行了定量评估。讨论了渗透压作用下细胞间连接结构重组的机制。提出了一个细胞间连接模型,该模型解释了渗透压作用下跨上皮电位差行为的基本特征。