Lee Sang Kil, Lee Yong Chan, Chung Jae Bock, Chon Chae Yoon, Moon Young Myoung, Kang Jin Kyung, Park In-Suh, Suh Chang Ok, Yang Woo Ik
Division of Gastroenterology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea.
World J Gastroenterol. 2004 Jan 15;10(2):223-6. doi: 10.3748/wjg.v10.i2.223.
To deduce strategic guidelines of gastric mucosa associated lymphoid tissue lymphoma (MALTOMA) by evaluating the long-term outcome of patients in respect to various treatment modalities.
A total of 55 patients with MALTOMA from May 1992 to August 2002 were retrospectively reviewed.
Complete remission was obtained in 24 (82.8%) of 29 patients treated with anti Helicobacter pylori (H pylori) regimen only. The duration to reach complete remission was 12 months (85 percentile, 2-33 months). Five patients showed complete remission with radiation therapy (26-86 months). Two of them were H pylori treatment failure cases.
H pylori eradication is an effective primary treatment option for low grade MALTOMA and radiation therapy could be considered in patients with no evidence of H pylori infection or who do not respond to H pylori eradication therapy 12 months after successful eradication.
通过评估不同治疗方式下患者的长期预后，推导胃黏膜相关淋巴组织淋巴瘤（MALTOMA）的治疗策略指南。
回顾性分析了1992年5月至2002年8月期间共55例MALTOMA患者的资料。
仅接受抗幽门螺杆菌（H pylori）治疗方案的29例患者中，24例（82.8%）实现完全缓解。达到完全缓解的时间为12个月（第85百分位数，2 - 33个月）。5例患者接受放射治疗后实现完全缓解（26 - 86个月）。其中2例为H pylori治疗失败病例。
根除幽门螺杆菌是低级别MALTOMA的有效初始治疗选择，对于无幽门螺杆菌感染证据或根除幽门螺杆菌治疗成功12个月后无反应的患者，可考虑放射治疗。
