Ratterree Marion S, da Rosa Amelia P A Travassos, Bohm Rudolf P, Cogswell Frank B, Phillippi Kathrine M, Caillouet Kevin, Schwanberger Shelle, Shope Robert E, Tesh Robert B
Tulane National Primate Research Center, Covington, Louisiana, USA.
Emerg Infect Dis. 2003 Nov;9(11):1388-94. doi: 10.3201/eid0911.030226.
During the summer of 2002, an epidemic of West Nile meningoencephalitis occurred in southern Louisiana. Following the outbreak, blood samples were collected from 1,692 captive rhesus monkeys (Macaca mulatta), pigtail macaques (M. nemestrina), and baboons (Papio spp.) that were permanently housed outdoors at a nonhuman primate breeding facility in St. Tammany Parish, Louisiana. The serum samples were examined for antibodies to West Nile virus (WNV). Overall, 36% of the captive nonhuman primates had WNV antibodies; comparison of these samples with banked serum samples from previous blood collections indicated that the animals were infected subclinically from February to August 2002. WNV activity was demonstrated in surveillance at the nonhuman primate-breeding colony and in the neighboring community during this same period. The high infection rate in this captive nonhuman primate population illustrates the intensity of WNV transmission that can occur silently in nature among other susceptible vertebrates during epidemic periods.
2002年夏季，路易斯安那州南部发生了西尼罗河脑膜脑炎疫情。疫情爆发后，从1692只圈养的恒河猴（猕猴）、豚尾猕猴和狒狒身上采集了血样，这些动物常年饲养在路易斯安那州圣塔曼尼教区的一个非人灵长类动物繁殖设施的户外。检测血清样本中的西尼罗河病毒（WNV）抗体。总体而言，36%的圈养非人灵长类动物有WNV抗体；将这些样本与之前采血保存的血清样本进行比较表明，这些动物在2002年2月至8月间受到了亚临床感染。同期在非人灵长类动物繁殖群体及邻近社区的监测中发现了WNV活动。该圈养非人灵长类动物群体的高感染率表明，在疫情期间，WNV可在自然界中其他易感脊椎动物间悄然传播。
