小家鼠中一种类BolA蛋白的溶液结构
Solution structure of a BolA-like protein from Mus musculus.
作者信息
Kasai Takuma, Inoue Makoto, Koshiba Seizo, Yabuki Takashi, Aoki Masaaki, Nunokawa Emi, Seki Eiko, Matsuda Takayoshi, Matsuda Natsuko, Tomo Yasuko, Shirouzu Mikako, Terada Takaho, Obayashi Naomi, Hamana Hiroaki, Shinya Naoko, Tatsuguchi Ayako, Yasuda Satoko, Yoshida Mayumi, Hirota Hiroshi, Matsuo Yo, Tani Kazutoshi, Suzuki Harukazu, Arakawa Takahiro, Carninci Piero, Kawai Jun, Hayashizaki Yoshihide, Kigawa Takanori, Yokoyama Shigeyuki
机构信息
Protein Research Group, RIKEN Genomic Sciences Center, 1-7-22 Suehiro-cho, Tsurumi, Yokohama 230-0045, Japan.
出版信息
Protein Sci. 2004 Feb;13(2):545-8. doi: 10.1110/ps.03401004. Epub 2004 Jan 10.
Abstract
The BolA-like proteins are widely conserved from prokaryotes to eukaryotes. The BolA-like proteins seem to be involved in cell proliferation or cell-cycle regulation, but the molecular function is still unknown. Here we determined the structure of a mouse BolA-like protein. The overall topology is alphabetabetaalphaalphabetaalpha, in which beta(1) and beta(2) are antiparallel, and beta(3) is parallel to beta(2). This fold is similar to the class II KH fold, except for the absence of the GXXG loop, which is well conserved in the KH fold. The conserved residues in the BolA-like proteins are assembled on the one side of the protein.
摘要
BolA样蛋白从原核生物到真核生物广泛保守。BolA样蛋白似乎参与细胞增殖或细胞周期调控，但其分子功能仍不清楚。在此我们确定了一种小鼠BolA样蛋白的结构。其整体拓扑结构为alphabetabetaalphaalphabetaalpha，其中β(1)和β(2)是反平行的，β(3)与β(2)平行。这种折叠与II类KH折叠相似，只是缺少在KH折叠中保守性良好的GXXG环。BolA样蛋白中的保守残基聚集在蛋白质的一侧。
相似文献
1
Solution structure of a BolA-like protein from Mus musculus.小家鼠中一种类BolA蛋白的溶液结构
Protein Sci. 2004 Feb;13(2):545-8. doi: 10.1110/ps.03401004. Epub 2004 Jan 10.
2
Solution-state NMR structure of the putative morphogene protein BolA (PFE0790c) from Plasmodium falciparum.恶性疟原虫假定形态发生蛋白BolA（PFE0790c）的溶液状态核磁共振结构。
Acta Crystallogr F Struct Biol Commun. 2015 May;71(Pt 5):514-21. doi: 10.1107/S2053230X1402799X. Epub 2015 Apr 18.
3
NMR solution structure of the archaebacterial chromosomal protein MC1 reveals a new protein fold.古细菌染色体蛋白MC1的核磁共振溶液结构揭示了一种新的蛋白质折叠方式。
Biochemistry. 2004 Nov 30;43(47):14971-8. doi: 10.1021/bi048382z.
4
Solution structure of the pro-hormone convertase 1 pro-domain from Mus musculus.小家鼠激素原转化酶1前结构域的溶液结构
J Mol Biol. 2002 Jul 19;320(4):801-12. doi: 10.1016/s0022-2836(02)00543-0.
5
A novel member of the YchN-like fold: solution structure of the hypothetical protein Tm0979 from Thermotoga maritima.YchN样折叠的一个新成员：来自海栖热袍菌的假定蛋白Tm0979的溶液结构
Protein Sci. 2005 Jan;14(1):216-23. doi: 10.1110/ps.041068605.
6
Structure of the nuclear factor ALY: insights into post-transcriptional regulatory and mRNA nuclear export processes.核因子ALY的结构：对转录后调控和mRNA核输出过程的深入了解
Biochemistry. 2003 Jun 24;42(24):7348-57. doi: 10.1021/bi034062o.
7
The solution structure of ribosomal protein L36 from Thermus thermophilus reveals a zinc-ribbon-like fold.嗜热栖热菌核糖体蛋白L36的溶液结构揭示了一种类似锌带的折叠结构。
J Mol Biol. 2000 Feb 11;296(1):169-80. doi: 10.1006/jmbi.1999.3433.
8
Solution structure of an atypical WW domain in a novel beta-clam-like dimeric form.一种新型β-蛤样二聚体形式的非典型WW结构域的溶液结构。
FEBS Lett. 2007 Feb 6;581(3):462-8. doi: 10.1016/j.febslet.2007.01.008. Epub 2007 Jan 16.
9
Solution structure of the RWD domain of the mouse GCN2 protein.小鼠GCN2蛋白RWD结构域的溶液结构
Protein Sci. 2004 Aug;13(8):2089-100. doi: 10.1110/ps.04751804.
10
Novel solution structure of porcine beta-microseminoprotein.猪β-微精蛋白的新型溶液结构
J Mol Biol. 2005 Mar 4;346(4):1071-82. doi: 10.1016/j.jmb.2004.12.029. Epub 2005 Jan 16.
引用本文的文献
1
Adaptation of the late ISC pathway in the anaerobic mitochondrial organelles of Giardia intestinalis.肠道贾第虫厌氧线粒体器官中晚期 ISC 途径的适应。
PLoS Pathog. 2023 Oct 4;19(10):e1010773. doi: 10.1371/journal.ppat.1010773. eCollection 2023 Oct.
2
New Perspectives on BolA: A Still Mysterious Protein Connecting Morphogenesis, Biofilm Production, Virulence, Iron Metabolism, and Stress Survival.BolA的新视角：一种连接形态发生、生物膜形成、毒力、铁代谢和应激存活的神秘蛋白质
Microorganisms. 2023 Mar 1;11(3):632. doi: 10.3390/microorganisms11030632.
3
Integrative analysis of the role of in human pan-cancer.对……在人类泛癌中的作用的综合分析 （原文“of”后面缺少具体内容）
Front Genet. 2023 Feb 27;14:1077126. doi: 10.3389/fgene.2023.1077126. eCollection 2023.
4
Full-Length Transcriptional Analysis of the Same Soybean Genotype With Compatible and Incompatible Reactions to Reveals Nematode Infection Activating Plant Defense Response.对同一大豆基因型与线虫相容性和不相容反应的全长转录分析揭示线虫感染激活植物防御反应。
Front Plant Sci. 2022 May 18;13:866322. doi: 10.3389/fpls.2022.866322. eCollection 2022.
5
Biochemical impact of a disease-causing Ile67Asn substitution on BOLA3 protein.疾病致病变异 Ile67Asn 对 BOLA3 蛋白的生化影响。
Metallomics. 2021 Apr 14;13(4). doi: 10.1093/mtomcs/mfab010.
6
NMR-Metabolomics Shows That BolA Is an Important Modulator of Typhimurium Metabolic Processes under Virulence Conditions.核磁共振代谢组学表明，BolA是鼠伤寒沙门氏菌在毒力条件下代谢过程的重要调节因子。
Metabolites. 2019 Oct 23;9(11):243. doi: 10.3390/metabo9110243.
7
A Vibrio cholerae BolA-Like Protein Is Required for Proper Cell Shape and Cell Envelope Integrity.霍乱弧菌 BolA 样蛋白对于维持细胞正常形态和细胞包膜完整性是必需的。
mBio. 2019 Jul 9;10(4):e00790-19. doi: 10.1128/mBio.00790-19.
8
Structural characterization of a novel KH-domain containing plant chloroplast endonuclease.一种新型 KH 结构域含有植物叶绿体核酸内切酶的结构特征。
Sci Rep. 2018 Sep 13;8(1):13750. doi: 10.1038/s41598-018-31142-w.
9
NMR as a Tool to Investigate the Processes of Mitochondrial and Cytosolic Iron-Sulfur Cluster Biosynthesis.NMR 作为研究线粒体和细胞质铁硫簇生物合成过程的工具。
Molecules. 2018 Aug 31;23(9):2213. doi: 10.3390/molecules23092213.
10
Stress Response Protein BolA Influences Fitness and Promotes Salmonella enterica Serovar Typhimurium Virulence.应激反应蛋白 BolA 影响沙门氏菌 Typhimurium 的适应性并促进其毒力。
Appl Environ Microbiol. 2018 Apr 2;84(8). doi: 10.1128/AEM.02850-17. Print 2018 Apr 15.
本文引用的文献
1
NMR View: A computer program for the visualization and analysis of NMR data.NMR 视图：用于可视化和分析 NMR 数据的计算机程序。
J Biomol NMR. 1994 Sep;4(5):603-14. doi: 10.1007/BF00404272.
2
Regulation of septation and cytokinesis during resumption of cell division requires uvi31+, a UV-inducible gene of fission yeast.
Mol Cells. 2002 Dec 31;14(3):425-30.
3
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.基于60770个全长cDNA功能注释的小鼠转录组分析。
Nature. 2002 Dec 5;420(6915):563-73. doi: 10.1038/nature01266.
4
The gene bolA regulates dacA (PBP5), dacC (PBP6) and ampC (AmpC), promoting normal morphology in Escherichia coli.基因bolA调控dacA（PBP5）、dacC（PBP6）和ampC（AmpC），促进大肠杆菌的正常形态形成。
Mol Microbiol. 2002 Sep;45(6):1729-40. doi: 10.1046/j.1365-2958.2002.03131.x.
5
Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA.KH结构域对序列特异性单链DNA识别的分子基础：hnRNP K KH3与单链DNA复合物的溶液结构
EMBO J. 2002 Jul 1;21(13):3476-85. doi: 10.1093/emboj/cdf352.
6
Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA.使用新软件CANDID和扭转角动力学算法DYANA进行自动NOE归属的蛋白质核磁共振结构测定。
J Mol Biol. 2002 May 24;319(1):209-27. doi: 10.1016/s0022-2836(02)00241-3.
7
Structure and dynamics of KH domains from FBP bound to single-stranded DNA.与单链DNA结合的FBP中KH结构域的结构与动力学
Nature. 2002 Feb 28;415(6875):1051-6. doi: 10.1038/4151051a.
8
Structural basis for recognition of the intron branch site RNA by splicing factor 1.剪接因子1识别内含子分支位点RNA的结构基础。
Science. 2001 Nov 2;294(5544):1098-102. doi: 10.1126/science.1064719.
9
Functional annotation of a full-length mouse cDNA collection.一个全长小鼠cDNA文库的功能注释
Nature. 2001 Feb 8;409(6821):685-90. doi: 10.1038/35055500.
10
KH domain: one motif, two folds.KH结构域：一种基序，两种折叠方式。
Nucleic Acids Res. 2001 Feb 1;29(3):638-43. doi: 10.1093/nar/29.3.638.
Zotero 插件