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NMR View: A computer program for the visualization and analysis of NMR data.NMR 视图：用于可视化和分析 NMR 数据的计算机程序。
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Regulation of septation and cytokinesis during resumption of cell division requires uvi31+, a UV-inducible gene of fission yeast.
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4
The gene bolA regulates dacA (PBP5), dacC (PBP6) and ampC (AmpC), promoting normal morphology in Escherichia coli.基因bolA调控dacA（PBP5）、dacC（PBP6）和ampC（AmpC），促进大肠杆菌的正常形态形成。
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Molecular basis of sequence-specific single-stranded DNA recognition by KH domains: solution structure of a complex between hnRNP K KH3 and single-stranded DNA.KH结构域对序列特异性单链DNA识别的分子基础：hnRNP K KH3与单链DNA复合物的溶液结构
EMBO J. 2002 Jul 1;21(13):3476-85. doi: 10.1093/emboj/cdf352.
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Protein NMR structure determination with automated NOE assignment using the new software CANDID and the torsion angle dynamics algorithm DYANA.使用新软件CANDID和扭转角动力学算法DYANA进行自动NOE归属的蛋白质核磁共振结构测定。
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Structural basis for recognition of the intron branch site RNA by splicing factor 1.剪接因子1识别内含子分支位点RNA的结构基础。
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Functional annotation of a full-length mouse cDNA collection.一个全长小鼠cDNA文库的功能注释
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KH domain: one motif, two folds.KH结构域：一种基序，两种折叠方式。
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小家鼠中一种类BolA蛋白的溶液结构

Solution structure of a BolA-like protein from Mus musculus.

作者信息

Kasai Takuma, Inoue Makoto, Koshiba Seizo, Yabuki Takashi, Aoki Masaaki, Nunokawa Emi, Seki Eiko, Matsuda Takayoshi, Matsuda Natsuko, Tomo Yasuko, Shirouzu Mikako, Terada Takaho, Obayashi Naomi, Hamana Hiroaki, Shinya Naoko, Tatsuguchi Ayako, Yasuda Satoko, Yoshida Mayumi, Hirota Hiroshi, Matsuo Yo, Tani Kazutoshi, Suzuki Harukazu, Arakawa Takahiro, Carninci Piero, Kawai Jun, Hayashizaki Yoshihide, Kigawa Takanori, Yokoyama Shigeyuki

机构信息

Protein Research Group, RIKEN Genomic Sciences Center, 1-7-22 Suehiro-cho, Tsurumi, Yokohama 230-0045, Japan.

出版信息

Protein Sci. 2004 Feb;13(2):545-8. doi: 10.1110/ps.03401004. Epub 2004 Jan 10.

DOI:10.1110/ps.03401004
PMID:14718656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2286707/
Abstract

The BolA-like proteins are widely conserved from prokaryotes to eukaryotes. The BolA-like proteins seem to be involved in cell proliferation or cell-cycle regulation, but the molecular function is still unknown. Here we determined the structure of a mouse BolA-like protein. The overall topology is alphabetabetaalphaalphabetaalpha, in which beta(1) and beta(2) are antiparallel, and beta(3) is parallel to beta(2). This fold is similar to the class II KH fold, except for the absence of the GXXG loop, which is well conserved in the KH fold. The conserved residues in the BolA-like proteins are assembled on the one side of the protein.

摘要

BolA样蛋白从原核生物到真核生物广泛保守。BolA样蛋白似乎参与细胞增殖或细胞周期调控，但其分子功能仍不清楚。在此我们确定了一种小鼠BolA样蛋白的结构。其整体拓扑结构为alphabetabetaalphaalphabetaalpha，其中β(1)和β(2)是反平行的，β(3)与β(2)平行。这种折叠与II类KH折叠相似，只是缺少在KH折叠中保守性良好的GXXG环。BolA样蛋白中的保守残基聚集在蛋白质的一侧。