Ortega-Moreno J, Caballero-Gómez J M
Department of Animal Pathology, University of Zaragoza, Spain.
Arch Gynecol Obstet. 1992;252(2):73-80. doi: 10.1007/BF02389631.
A one centimeter length of the left uterine horn in two groups of Wistar rats (n = 10) was replaced with normal (VAS group) or with denervated and devascularizated (NVAS group) colonic grafts. All animals maintained pregnancy in the right control horns but not in the grafted horns. At 40, 60 and 90 days after surgery, the light microscopic appearance of the autografts was studied. In the VAS group, and with respect to the last period, the number (5.5 +/- 0.7) and height (1.0 +/- 0.1 mm, P < 0.05 ANOVA) of the folds, the intestinal glands height (160.2 +/- 21.2 mu, P < 0.05 ANOVA) and the number of globet cells per gland (26.6 +/- 4.2, P < 0.05 ANOVA) had decreased in relation to the colon control (6.0 +/- 0.7, 1.4 +/- 0.1, 251.7 +/- 31.8, 42.6 +/- 5.2 respectively). A similar intestinal structure to that described above was observed in the anastomosis areas of the NVAS group, and therefore a decreased mucus production was maintained in this areas. No folds or intestinal glands were observed, but a monoestratified cubic epithelial cells type was observed along 63.7 +/- 4.1% of the NVAS colonic graft center. Under this epithelium a connective tissue, like a non-glandular submucosa, was obtained.
在两组Wistar大鼠（n = 10）中，用正常结肠移植物（VAS组）或去神经和去血管化结肠移植物（NVAS组）替换左子宫角1厘米长的组织。所有动物右侧对照子宫角维持妊娠，但移植子宫角未维持妊娠。在术后40、60和90天，研究自体移植物的光镜外观。在VAS组，与最后一个时期相比，皱襞数量（5.5±0.7）和高度（1.0±0.1毫米，方差分析P<0.05）、肠腺高度（160.2±21.2微米，方差分析P<0.05）以及每个腺体内杯状细胞数量（26.6±4.2，方差分析P<0.05）相对于结肠对照（分别为6.0±0.7、1.4±0.1、251.7±31.8、42.6±5.2）均有所减少。在NVAS组的吻合区域观察到与上述相似的肠道结构，因此该区域黏液分泌减少。未观察到皱襞或肠腺，但在NVAS结肠移植物中心63.7±4.1%的区域观察到单层立方上皮细胞类型。在此上皮下方获得了一种类似非腺性黏膜下层的结缔组织。
