Sokolova R I, Volkov V N, Bulkina O S, Ustinova S E
Arkh Patol. 1992;54(7):30-3.
The study of structural changes and changes of the aldosterone content (AC) in the surgically removed adrenals of patients with different clinical variants of combination of the arterial hypertension (AH), low--renin hyperaldosteronism and space--occupying lesions in the adrenals found by CT was carried out. In 15 of 20 patients after adrenalectomy the diagnosis of the primary aldosteronism (PA) was established, in 4 cases diagnosis of the hypertension, 2B degree, and in one case the diagnosis of Cushing disease. The functional state was evaluated according to AC in the adenomas and macronodes and in the adjacent cortex as well as by nuclei size of cells producing aldosterone. The aldosterone hyperproduction was shown to be associated with local adenoma in some cases and with hyperactive cortex in the others this being reflected in the course of AH and in the adrenalectomy hypotensive effect.
对经CT检查发现肾上腺有占位性病变、患有动脉高血压（AH）、低肾素性醛固酮增多症不同临床组合的患者，其手术切除肾上腺的结构变化及醛固酮含量（AC）变化进行了研究。20例患者中，15例在肾上腺切除术后确诊为原发性醛固酮增多症（PA），4例诊断为2级高血压，1例诊断为库欣病。根据腺瘤和大结节以及相邻皮质中的AC以及产生醛固酮的细胞的核大小评估功能状态。结果显示，醛固酮分泌过多在某些情况下与局部腺瘤有关，而在其他情况下与皮质功能亢进有关，并反映在AH病程及肾上腺切除术后的降压效果中。
