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[原发性醛固酮增多症一例。病例报告]

[A case of primary hyperaldosteronism. Case report].

作者信息

Bulfoni A, Gobbato F

出版信息

Arch Sci Med (Torino). 1979 Oct-Dec;136(4):643-52.

PMID:550763
Abstract

The authors discuss a reported case of primary aldosteronism, which is relatively uncommon within hypertensive population. The diagnosis of primary aldosteronism must be suggested by the presence of the association of arterial hypertension and hypokaliemia, which nevertheless is not pathognomonic. It is emphasized the significance of the detection of this syndrome on account of the correction following surgical removal of the adenoma of the adrenal cortex. Two attacks of paroxismal hypertension, which are atypical in primary aldosteronism, had been observed in the reported case; however, apart from these exceptions, arterial hypertension has resulted generally constant and of moderate degree, as well as the majority of the others descriptions. The personal experience confirms the need to determine plasma levels of renin and aldosterone before the therapeutic or diagnostic use of spironolactone.

摘要

作者讨论了一例原发性醛固酮增多症的报告病例,该病在高血压人群中相对不常见。原发性醛固酮增多症的诊断必须通过动脉高血压和低钾血症的联合表现来提示,不过这并非是该病的特征性表现。强调了检测该综合征的重要性,因为肾上腺皮质腺瘤手术切除后症状会得到改善。在所报告的病例中观察到了两次阵发性高血压发作,这在原发性醛固酮增多症中并不典型;然而,除了这些例外情况,动脉高血压通常一直存在且程度中等,其他大多数描述也是如此。个人经验证实,在使用螺内酯进行治疗或诊断之前,有必要测定血浆肾素和醛固酮水平。

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