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诺如病毒、札幌样病毒和A组轮状病毒胃肠炎的危险因素。

Risk factors for norovirus, Sapporo-like virus, and group A rotavirus gastroenteritis.

作者信息

de Wit Matty A S, Koopmans Marion P G, van Duynhoven Yvonne T H P

机构信息

National Institute of Public Health and the Environment, Bilthoven, The Netherlands.

出版信息

Emerg Infect Dis. 2003 Dec;9(12):1563-70. doi: 10.3201/eid0912.020076.

Abstract

Viral pathogens are the most common causes of gastroenteritis in the community. To identify modes of transmission and opportunities for prevention, a case-control study was conducted and risk factors for gastroenteritis attributable to norovirus (NV), Sapporo-like virus (SLV), and rotavirus were studied. For NV gastroenteritis, having a household member with gastroenteritis, contact with a person with gastroenteritis outside the household, and poor food-handling hygiene were associated with illness (population attributable risk fractions [PAR] of 17%, 56%, and 47%, respectively). For SLV gastroenteritis, contact with a person with gastroenteritis outside the household was associated with a higher risk (PAR 60%). For rotavirus gastroenteritis, contact with a person with gastroenteritis outside the household and food-handling hygiene were associated with a higher risk (PAR 86% and 46%, respectively). Transmission of these viral pathogens occurs primarily from person to person. However, for NV gastroenteritis, foodborne transmission seems to play an important role.

摘要

病毒病原体是社区中肠胃炎最常见的病因。为了确定传播方式和预防机会,开展了一项病例对照研究,并对由诺如病毒(NV)、札幌样病毒(SLV)和轮状病毒引起的肠胃炎的危险因素进行了研究。对于NV肠胃炎,家中有肠胃炎患者、与家庭外的肠胃炎患者接触以及食品处理卫生差与患病有关(人群归因危险度分别为17%、56%和47%)。对于SLV肠胃炎,与家庭外的肠胃炎患者接触会增加患病风险(人群归因危险度60%)。对于轮状病毒肠胃炎,与家庭外的肠胃炎患者接触和食品处理卫生与患病风险增加有关(人群归因危险度分别为86%和46%)。这些病毒病原体主要通过人与人之间传播。然而,对于NV肠胃炎,食源性传播似乎起着重要作用。

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