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原发性心脏T细胞淋巴瘤

Primary cardiac T-cell lymphoma.

作者信息

Giunta Riccardo, Cravero Ranieri G, Granata Gianluca, Sellitto Ausilia, Romano Ciro, De Fanis Umberto, Foccillo Giampiero, De Capite Cleofina, Santini Mario, Rossiello Luigi, Rossiello Raffaele, Lucivero Giacomo

机构信息

Division of Internal Medicine, Allergy and Clinical Immunology, Department of Gerontology, Geriatrics and Metabolic Diseases, Second University of Naples School of Medicine, Italy.

出版信息

Ann Hematol. 2004 Jul;83(7):450-4. doi: 10.1007/s00277-003-0824-9. Epub 2004 Jan 14.

Abstract

Primary cardiac lymphoma (PCL), defined as a lymphoma clinically mimicking cardiac disease, with the bulk of the tumor located intrapericardially, is extremely rare in immunocompetent patients. Clinical manifestations vary depending on sites of involvement in the heart and include chest pain, arrhythmias, pericardial effusion, and heart failure. Diagnosis is often difficult and may require invasive procedures; in some cases, diagnosis is not made until autopsy. Histologically, nearly all cases of PCL reported thus far have been of B-cell origin. In this report, we describe a case of PCL of T-cell origin in an adult immunocompetent patient, the second reported in the literature to the best of our knowledge, and provide a brief overview of the features of previously published PCL cases.

摘要

原发性心脏淋巴瘤(PCL)被定义为临床上类似心脏病的淋巴瘤,肿瘤大部分位于心包内,在免疫功能正常的患者中极为罕见。临床表现因心脏受累部位而异,包括胸痛、心律失常、心包积液和心力衰竭。诊断往往困难,可能需要进行侵入性检查;在某些情况下,直到尸检才得以确诊。从组织学上看,迄今为止报道的几乎所有PCL病例均为B细胞起源。在本报告中,我们描述了一例成年免疫功能正常患者的T细胞起源的PCL病例,据我们所知这是文献中报道的第二例,并简要概述了先前发表的PCL病例的特征。

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