Highly restricted BMP10 expression in the trabeculating myocardium of the chick embryo.

Bone morphogenetic proteins (BMPs) control the development of diverse tissues during embryogenesis. Here, we report the expression of the BMP10 gene during chick development. BMP10 transcription is confined to the myocardium of atriae and ventricles in the forming heart from day 2 of development onwards (stage HH13). It correlates with the thickening of the innermost layer of the walls, i.e. the formation of myocardial ridges or trabeculae.