Schütz Harald, Verhoff Marcel A, Erdmann Freidoon, Weiler Günter
Institut für Rechtsmedizin der Universität Giessen.
Arch Kriminol. 2003 Nov-Dec;212(5-6):141-50.
The article describes problems related to immunochemical screening-tests with special regard to benzodiazepines, which are commonly used for therapeutic purposes. Focal points are adulteration, manipulation and handling of samples, the selection of cut-off-values, specificity and cross-reactivity, influence of biotransformation and frequently observed pitfalls in the interpretation of the analytical results.
本文描述了与免疫化学筛查试验相关的问题,特别关注常用于治疗目的的苯二氮䓬类药物。重点包括样本的掺假、处理和操作、临界值的选择、特异性和交叉反应性、生物转化的影响以及分析结果解释中常见的陷阱。