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五种用于现场滥用药物筛查的快速检测试剂盒的初步评估。

A preliminary evaluation of five rapid detection kits for on site drugs of abuse screening.

作者信息

George S, Braithwaite R A

机构信息

Regional Laboratory for Toxicology, City Hospital NHS Trust, Birmingham, UK.

出版信息

Addiction. 1995 Feb;90(2):227-32.

PMID:7703816
Abstract

There are now several rapid drugs of abuse testing kits that have been designed for near-patient testing and on-site clinic screening for drug abuse. These kits are sold on the basis of their cost and rapid generation of accurate results. Five such kits have been evaluated by comparison with recognized and established methodologies. All of the kits evaluated were found to lack both sensitivity and specificity. An unacceptable proportion of false negative and false positive results were observed for most kits. This raises the question of their usefulness in the near-patient and clinic situation.

摘要

现在有几种用于药物滥用快速检测的试剂盒,这些试剂盒是为患者床边检测和现场诊所药物滥用筛查而设计的。这些试剂盒因其成本低且能快速得出准确结果而得以销售。通过与公认的既定方法进行比较,对五种此类试剂盒进行了评估。结果发现,所有评估的试剂盒均缺乏敏感性和特异性。大多数试剂盒都出现了不可接受比例的假阴性和假阳性结果。这就引发了它们在患者床边和诊所环境中实用性的问题。

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