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[从合并念珠菌病的广泛性牙周炎患者中分离出的酵母的定量、种类组成及抗真菌药敏性研究]

[Investigation of quantitative and species composition and antifungal drug susceptibility of yeasts isolated from patients with generalized periodontitis complicated by candidosis].

作者信息

Kutsyk R V, Pavliuk T D

机构信息

Ivano-Frankivsk State Medical Academy, 2 Galytska St., Ivano-Frankivsk, 76000, Ukraine.

出版信息

Mikrobiol Z. 2003 Sep-Oct;65(5):26-9.

PMID:14723159
Abstract

Biological properties of 68 Candida strains isolated from parodontal pockets of patients with generalized parodontitis complicated with candidosis have been investigated. It was established that 72.1 +/- 5.43% of strains belong to Candida albicans. The clinical Candida albicans isolates display high resistance to nystatin and levorin, but they are sensitive to synthetic antifungal drugs 5-fluorocytosine, fluconazol, especially to ketoconazol, itraconazole and to antifungal antibiotic amphotericin B as well.

摘要

对从患有广泛性牙周炎合并念珠菌病患者的牙周袋中分离出的68株念珠菌菌株的生物学特性进行了研究。结果确定,72.1±5.43%的菌株属于白色念珠菌。临床分离的白色念珠菌菌株对制霉菌素和利伏菌素表现出高度耐药性,但它们对合成抗真菌药物5-氟胞嘧啶、氟康唑敏感,尤其对酮康唑、伊曲康唑以及抗真菌抗生素两性霉素B也敏感。

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