艾滋病患者急性呼吸窘迫的一种罕见病因：刚地弓形虫原发性感染。

An unusual cause of acute respiratory distress in a patient with AIDS: primary infection with Toxoplasma gondii.

作者信息

Charles Pierre Emmanuel, Doise Jean Marc, Quenot Jean Pierre, Aube Herve, Dalle Frederic, Bour Jean Baptiste, Chavanet Pascal, Blettery Bernard

机构信息

Service de Reanimation Médicale, Dijon University Hospital, Dijon, France.

出版信息

Scand J Infect Dis. 2003;35(11-12):901-2. doi: 10.1080/00365540310017050.

DOI:10.1080/00365540310017050

PMID:14723378

Abstract

Hypoxemic pneumonia in AIDS patients is mainly caused by Pneumocystis carinii, Toxoplasma gondii and CMV, although the significance of CMV recovery in BALF is often unclear. Since lung involvement generally occurs during reactivation, T. gondii is not expected to be demonstrated in patients without evidence of past infection with this agent. We report a fatal case of pneumonia revealing a T. gondii primary infection diagnosed thanks to the PCR analysis of the BALF.

摘要

艾滋病患者的低氧血症性肺炎主要由卡氏肺孢子虫、弓形虫和巨细胞病毒引起，尽管巨细胞病毒在支气管肺泡灌洗（BALF）中恢复的意义通常尚不清楚。由于肺部受累通常发生在再激活期间，因此在没有该病原体既往感染证据的患者中预计不会检测到弓形虫。我们报告了一例致命性肺炎病例，通过对BALF进行PCR分析诊断为弓形虫原发性感染。