Ungpakorn R, Lohaprathan S, Reangchainam S
Mycology Division, Institute of Dermatology, Bangkok, Thailand.
Clin Exp Dermatol. 2004 Jan;29(1):87-90. doi: 10.1111/j.1365-2230.2004.01446.x.
Two thousand patients who visited the outpatient department at the Institute of Dermatology, Bangkok, were assessed for the presence of foot diseases by questionnaire and physical examination. Abnormalities were detected in 741 individuals (37.1%). Nonfungal conditions were more prevalent (31.4%), mainly consisting of eczema (254 cases, 12.7%) and psoriasis (176 cases, 8.8%). Fungal disease was observed in 119 cases (6.0%). There were 76 cases (3.8%) with tinea pedis and 33 cases (1.7%) with onychomycosis. The identified organisms causing tinea pedis were 57.9% nondermatophyte moulds, 36.8% dermatophytes, and 2.6%Candida spp. The corresponding organisms causing onychomycosis were 51.6% nondermatophyte moulds, 36.3% dermatophytes, and 6.0%Candida spp. Among nondermatophytes, Scytalidium dimidiatum was the leading pathogen while Trichophyton rubrum and T. mentagrophytes were the predominant dermatophytes identified. Diabetes mellitus, peripheral vascular disease and activities related to foot trauma were noted to be predisposing factors for onychomycosis. Footwear, particularly sandals and cut shoes, was the only factor relevant to individuals with tinea pedis (P < or = 0.05). In contrast with other published data on fungal foot infections, this study disclosed a higher prevalence of nondermatophyte organisms, predominantly S. dimidiatum, as the major cause of tinea pedis and onychomycosis. An increase in awareness is necessary to identify such cases, prevent misdiagnosis and initiate appropriate treatment.
通过问卷调查和体格检查,对2000名前往曼谷皮肤病研究所门诊部就诊的患者进行了足部疾病检查。741人(37.1%)被检测出异常。非真菌性疾病更为常见(31.4%),主要包括湿疹(254例,12.7%)和银屑病(176例,8.8%)。观察到11例(6.0%)真菌性疾病。足癣76例(3.8%),甲癣33例(1.7%)。引起足癣的病原菌中,57.9%为非皮肤癣菌霉菌,36.8%为皮肤癣菌,2.6%为念珠菌属。引起甲癣的相应病原菌中,51.6%为非皮肤癣菌霉菌,36.3%为皮肤癣菌,6.0%为念珠菌属。在非皮肤癣菌中,指间毛癣菌是主要病原菌,而红色毛癣菌和须癣毛癣菌是主要鉴定出的皮肤癣菌。糖尿病、外周血管疾病以及与足部创伤相关的活动被认为是甲癣的易感因素。鞋类,尤其是凉鞋和破鞋,是与足癣患者相关的唯一因素(P≤0.05)。与其他已发表的关于足部真菌感染的数据相比,本研究发现非皮肤癣菌,主要是指间毛癣菌,作为足癣和甲癣的主要病因的患病率更高。有必要提高认识以识别此类病例,防止误诊并启动适当治疗。