Doye Valérie
Nuclear Pores and Nucleocytoplasmic Transport, UMR144 CNRS-Institut Curie, 26, rue d'Ulm, 75248 Paris edex 05, France.
Dev Cell. 2004 Jan;6(1):1-3. doi: 10.1016/s1534-5807(03)00405-2.
Until now, regulation of nucleocytoplasmic transport of macromolecules has been thought to occur mainly through modifications of the cargo molecules. However, in the December 26 issue of Cell, Makhnevych et al. describe a novel mechanism controlling cell cycle progression in yeast that involves subtle molecular rearrangements within the nuclear pore complexes.
到目前为止，人们一直认为大分子的核质运输调控主要通过货物分子的修饰来实现。然而，在12月26日的《细胞》杂志上，马赫涅维奇等人描述了一种控制酵母细胞周期进程的新机制，该机制涉及核孔复合物内微妙的分子重排。
