尽管大脑中动脉闭塞，但仍有轻微神经症状。
Mild neurological symptoms despite middle cerebral artery occlusion.
作者信息
Coutts Shelagh B, Barber Philip A, Demchuk Andrew M, Hill Michael D, Pexman J H Warwick, Hudon Mark E, Buchan Alastair M
机构信息
Department of Clinical Neurosciences, University of Calgary, Alberta T2N 2T9, Canada.
出版信息
Stroke. 2004 Feb;35(2):469-71. doi: 10.1161/01.STR.0000110985.01773.7F. Epub 2004 Jan 15.
BACKGROUND AND PURPOSE
Only a small percentage of stroke patients are treated with thrombolytic therapy. We sought to determine whether vessel occlusion in mild strokes represented a new target population for interventional therapy.
METHODS
We imaged 106 acute stroke patients with MRI. Patients were identified with evidence of middle cerebral artery (MCA) occlusion and mild or no stroke signs (National Institutes of Health Stroke Scale [NIHSS] <or=3). They were compared with patients with signs of stroke, NIHSS >3, and MCA occlusion.
RESULTS
We identified 5 patients with absent flow on MRA in the MCA and mild or no stroke signs (NIHSS <or=3). All 5 were functionally independent at 3 months.
CONCLUSIONS
Caution should be exercised in considering thrombolytic therapy in these patients. Quantification of perfusion imaging is required to identify "at risk" mild stroke populations.
背景与目的
仅有一小部分中风患者接受了溶栓治疗。我们试图确定轻度中风中的血管闭塞是否代表了介入治疗的新目标人群。
方法
我们对106例急性中风患者进行了MRI成像。确定患者存在大脑中动脉（MCA）闭塞且有轻度或无中风体征（美国国立卫生研究院卒中量表[NIHSS]≤3）。将他们与有中风体征、NIHSS>3且有MCA闭塞的患者进行比较。
结果
我们在MCA的MRA上发现5例血流缺失且有轻度或无中风体征（NIHSS≤3）的患者。所有5例患者在3个月时功能均独立。
结论
在考虑对这些患者进行溶栓治疗时应谨慎。需要对灌注成像进行量化以识别“有风险”的轻度中风人群。
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