Cantatore Julie L, Kriegel David A
Department of Peadiatrics, North Shore-Long Island Jewish Health System, New Hyde Park, New York, USA.
J Am Acad Dermatol. 2004 Feb;50(2):165-84; quiz 185-8. doi: 10.1016/j.jaad.2003.08.004.
Revolutionary advances in laser research and technology have led to expanded dermatologic laser applications. With the wide range of lasers now available, a large spectrum of skin conditions in the pediatric population can be successfully treated or, in some cases, completely eradicated. Laser treatment of the pediatric population poses a unique challenge for the clinician on a variety of levels. Physically, the composition of many vascular and pigmented lesions changes as children age making them more resistant to laser therapy. Thus, in many cases, treating lesions at an early age has resulted in clearing in fewer sessions and with decreased complications. Mechanically, lasers and laser settings used for the treatment of adult lesions may have to be adjusted for the smaller vessels and the unpredictable nature of scarring with children's skin. For vascular lesions, the pulsed dye laser is considered the laser of choice for its efficacy and low-risk profile, whereas the Q-switched, pigment-specific lasers are ideal for most childhood pigmented lesions, allowing for single pigment cell destruction. Other conditions such as acne and acne scars, psoriasis, keloids, warts and hypertrichosis that traditionally have been treated with a variety of modalities are now being managed safely with laser surgery. Other issues specific to the pediatric population include the determination of suitable anesthesia, the provision of size-appropriate safety equipment, and the assessment and management of patient and parent anxiety. The use of lasers specifically designed for structural differences in pediatric lesions and the recognition of emotional issues surrounding a young patient during laser surgery are critical components of successful treatment.
At the conclusion of this learning activity, participants should be familiar with the mechanism of laser technology, current trends in the use of lasers for skin lesions in the pediatric population, and the issues specific to treating a patient with laser surgery.
激光研究与技术的革命性进展带来了皮肤科激光应用的扩展。如今有多种激光可供选择,儿科人群中的大量皮肤疾病能够得到成功治疗,在某些情况下甚至可被完全根除。对临床医生而言,儿科人群的激光治疗在多个层面都构成了独特挑战。从生理角度看,许多血管性和色素性病变的构成会随着儿童年龄增长而变化,这使得它们对激光治疗更具抵抗力。因此,在许多情况下,早期治疗病变所需的疗程更少,并发症也更少。从机械角度看,用于治疗成人病变的激光及激光设置可能需要针对儿童较小的血管和儿童皮肤瘢痕形成的不可预测性进行调整。对于血管性病变,脉冲染料激光因其疗效和低风险特性被视为首选激光,而调Q、针对色素的激光对大多数儿童色素性病变而言是理想选择,能够破坏单个色素细胞。其他诸如痤疮及痤疮瘢痕、银屑病、瘢痕疙瘩、疣和多毛症等传统上采用多种方式治疗的疾病,如今也可通过激光手术安全治疗。儿科人群特有的其他问题包括确定合适的麻醉方式、提供尺寸合适的安全设备以及评估和处理患者及家长的焦虑情绪。使用专门针对儿科病变结构差异设计的激光以及认识到激光手术期间围绕年轻患者的情感问题,是成功治疗的关键要素。
在本次学习活动结束时,参与者应熟悉激光技术的机制、儿科人群皮肤病变激光治疗的当前趋势以及激光手术治疗患者所特有的问题。