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挪威反刍动物中的瘟病毒感染

Pestivirus infections in ruminants in Norway.

作者信息

Løken T

机构信息

National Veterinary Institute, Oslo, Norway.

出版信息

Rev Sci Tech. 1992 Sep;11(3):895-9.

PMID:1472734
Abstract

Serological surveys in Norway have demonstrated neutralising antibodies against bovine virus diarrhoea (BVD) virus in cattle, sheep and goats. The prevalences were 18.5%, 4.5% and 3.6%, respectively. Occurrence of pestivirus-induced disease in Norway is described. Outbreaks of reproductive failure and mucosal disease have been reported, and the number of persistently-infected animals detected has increased considerably in recent years. Acute BVD occurs rarely. Border disease (BD) in sheep, first diagnosed in 1981, has subsequently been demonstrated sporadically. In goats, typical BD was diagnosed in 1982, with three later occurrences of reproductive failure. Experimental infections in pregnant goats induced a high rate of severe foetopathogenic effect. Signs and lesions in offspring were comparable to ovine BD. Similar findings were demonstrated in goats given a pestivirus-contaminated vaccine. In newborn kids, experimental infection had an adverse influence on growth and health. Persistent infection in goats is probably rare.

摘要

挪威的血清学调查表明,牛、绵羊和山羊体内存在针对牛病毒性腹泻(BVD)病毒的中和抗体。其流行率分别为18.5%、4.5%和3.6%。文中描述了挪威瘟病毒引起的疾病情况。已报告了繁殖障碍和黏膜病的暴发,近年来检测到的持续感染动物数量大幅增加。急性BVD很少发生。绵羊的边界病(BD)于1981年首次确诊,随后呈散发性出现。1982年在山羊中诊断出典型的BD,之后又有3次繁殖障碍发生。对怀孕山羊进行实验性感染导致了很高比例的严重胎儿致病效应。后代的症状和病变与绵羊BD相似。给山羊接种受瘟病毒污染的疫苗也出现了类似结果。在新生山羊羔中,实验性感染对生长和健康有不利影响。山羊中的持续感染可能很少见。

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