Klapper David A, Weaver Joshua, Fernandez Hubert, Ohno-Machado Lucila
Brigham and Women's Hospital, Boston, MA, USA.
AMIA Annu Symp Proc. 2003;2003:896.
For Parkinson's patients to function at their best, the clinicians who care for them must be able to manage and offset the fluctuations in movement that occur throughout the day. Symptoms of Parkinsonism such as bradykinesia, hypokinesia and akinesia and medication-related side effects such as dyskinesia need to be reported to the clinician in a manner that accurately conveys the timing and severity of symptoms. The clinician can then tightly adjust and titrate the timing and dosing of medication, allowing the patient to function at his or her best. Patient history and patient self reporting diaries are currently used for this purpose, but they have problems with compliance, completeness and reliability. A monitor that could be worn by the patient while he or she is at home and could issue to the clinician a report of how the patient has been moving over the course of the day would be a great help to clinicians. Wearable devices have been studied for the measurement of movement in Parkinson's patients, but none have been designed in a manner that would be useful for the titration of medications 1, 2, 3.
为使帕金森病患者发挥出最佳功能，照料他们的临床医生必须能够管理并抵消全天出现的运动波动。帕金森综合征的症状，如运动迟缓、运动减退和运动不能，以及与药物相关的副作用，如运动障碍，需要以准确传达症状发生时间和严重程度的方式报告给临床医生。然后，临床医生可以严格调整并滴定药物的时间和剂量，使患者发挥出最佳功能。目前，患者病史和患者自我报告日记用于此目的，但它们在依从性、完整性和可靠性方面存在问题。一种患者在家时可以佩戴，并能向临床医生提供患者一天中运动情况报告的监测器，将对临床医生有很大帮助。可穿戴设备已被用于研究帕金森病患者的运动测量，但尚无设计方式对药物滴定有用的设备。
