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本文引用的文献

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Changes in liver-specific compared to common gene transcription during primary culture of mouse hepatocytes.小鼠肝细胞原代培养过程中肝脏特异性基因与常见基因转录的变化。
Mol Cell Biol. 1983 Sep;3(9):1552-61. doi: 10.1128/mcb.3.9.1552-1561.1983.
2
Hepatocyte proliferation in vitro: its dependence on the use of serum-free hormonally defined medium and substrata of extracellular matrix.体外肝细胞增殖：其对无血清激素限定培养基及细胞外基质底物使用的依赖性。
Proc Natl Acad Sci U S A. 1984 Mar;81(5):1411-5. doi: 10.1073/pnas.81.5.1411.
3
Posttranscriptional modulation of gene expression in cultured rat hepatocytes.培养的大鼠肝细胞中基因表达的转录后调控
Mol Cell Biol. 1984 Sep;4(9):1929-34. doi: 10.1128/mcb.4.9.1929-1934.1984.
4
Regulation of growth and differentiation of a rat hepatoma cell line by the synergistic interactions of hormones and collagenous substrata.激素与胶原基质的协同相互作用对大鼠肝癌细胞系生长和分化的调控
J Cell Biol. 1983 Oct;97(4):1179-90. doi: 10.1083/jcb.97.4.1179.
5
Liver-specific RNA metabolism in hepatoma cells: variations in transcription rates and mRNA levels.肝癌细胞中肝脏特异性RNA代谢：转录速率和mRNA水平的变化
Mol Cell Biol. 1985 Oct;5(10):2633-41. doi: 10.1128/mcb.5.10.2633-2641.1985.
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Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.
Cell. 1987 Apr 10;49(1):121-9. doi: 10.1016/0092-8674(87)90762-8.
7
Position-independent, high-level expression of the human beta-globin gene in transgenic mice.人β-珠蛋白基因在转基因小鼠中与位置无关的高水平表达。
Cell. 1987 Dec 24;51(6):975-85. doi: 10.1016/0092-8674(87)90584-8.
8
Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids.基因座激活区域的证据：在表达珠蛋白的杂种中形成发育稳定的超敏位点。
Nucleic Acids Res. 1987 Dec 23;15(24):10159-77. doi: 10.1093/nar/15.24.10159.
9
Expression of human alpha 1-acid glycoprotein genes in cultured cells and in transgenic mice.人α1-酸性糖蛋白基因在培养细胞和转基因小鼠中的表达。
Genes Dev. 1988 Feb;2(2):259-66. doi: 10.1101/gad.2.2.259.
10
The muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancer.肌肉肌酸激酶基因受多个上游元件调控，包括一个肌肉特异性增强子。
Mol Cell Biol. 1988 Jan;8(1):62-70. doi: 10.1128/mcb.8.1.62-70.1988.

Discordance between gene regulation in vitro and in vivo.

作者信息

Kitsis R N, Leinwand L A

机构信息

Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461.

出版信息

Gene Expr. 1992;2(4):313-8.

PMID:1472867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6057365/
Abstract
摘要