Tsonis Panagiotis A, Del Rio-Tsonis Katia
University of Dayton, Laboratory of Molecular Biology, Department of Biology, Dayton, OH 45469-2320, USA.
Exp Eye Res. 2004 Feb;78(2):161-72. doi: 10.1016/j.exer.2003.10.022.
In this review we present a synthesis on the potential of vertebrate eye tissue regeneration, such as lens and retina. Particular emphasis is given to two different strategies used for regeneration, transdifferentiation and stem cells. Similarities and differences between these two strategies are outlined and it is proposed that both strategies might follow common pathways. Furthermore, we elaborate on specific clinical applications as the outcome of regeneration-based research.
在本综述中，我们对脊椎动物眼组织（如晶状体和视网膜）再生的潜力进行了综合阐述。特别强调了用于再生的两种不同策略，即转分化和干细胞。概述了这两种策略之间的异同，并提出这两种策略可能遵循共同的途径。此外，我们详细阐述了基于再生研究成果的具体临床应用。
