Cole Martin G
Department of Psychiatry, St. Mary's Hospital and McGill University, Montreal, Quebec Canada.
Am J Geriatr Psychiatry. 2004 Jan-Feb;12(1):7-21.
Delirium is a mental disorder characterized by disturbances in consciousness, orientation, memory, thought, perception, and behavior, of acute onset and fluctuating course. It occurs in hyperactive, hypoactive, or mixed forms, in up to 50% of elderly hospital inpatients, many with pre-existing dementia, and appears to be independently associated with significant increases in functional disability, length of hospital stay, rates of admission to long-term care institutions, rates of death, and healthcare costs. Despite its clinical importance, delirium is often not detected or it is misdiagnosed as dementia or other psychiatric illness even though there are potential strategies (e.g., screening by nurses, risk-factor assessment) and instruments that can improve detection and diagnosis. Although there has been limited progress in understanding the etiology, pathogenesis, assessment, and specific treatment of delirium, systematic detection and treatment programs appear to be beneficial for elderly surgical patients, as are preventive programs for elderly medical and surgical patients. Even now, there is probably enough evidence to recommend implementation of these two types of programs in acute-care hospitals.
谵妄是一种精神障碍,其特征为意识、定向、记忆、思维、感知及行为出现紊乱,起病急且病程波动。它有活动亢进型、活动减退型或混合型等形式,在多达50%的老年住院患者中出现,其中许多人已有痴呆症,而且似乎与功能残疾显著增加、住院时间延长、入住长期护理机构的比率、死亡率以及医疗费用独立相关。尽管谵妄具有临床重要性,但即便存在能提高其检出率和诊断率的潜在策略(如护士筛查、风险因素评估)及工具,谵妄往往仍未被发现,或者被误诊为痴呆症或其他精神疾病。虽然在理解谵妄的病因、发病机制、评估及特异性治疗方面进展有限,但系统的检测和治疗方案似乎对老年外科患者有益,针对老年内科和外科患者的预防方案亦是如此。即便在当下,或许已有足够证据推荐在急症医院实施这两类方案。