Institute of Nursing Science, University of Freiburg, Faculty of Medicine, Freiburg, Germany.
Department of Medicine II, University Hospital Freiburg, Freiburg, Germany.
Z Gastroenterol. 2023 Oct;61(10):1357-1364. doi: 10.1055/a-2124-1874. Epub 2023 Aug 16.
Prevalence rates of delirium amount to 22.0% within acute-care settings. In contrast, 30-40% of patients with liver cirrhosis may develop hepatic encephalopathy, a condition that has been classified as a syndrome of delirium, based on recent pathophysiology findings. However, the prevalence of delirium in gastroenterology and hepatology units is unknown.The aims of the study were (i) to identify delirium prevalence rates in inpatients of gastroenterology/hepatology wards, (ii) to analyze the delirium motor subtype, and (iii) to assess associations between delirium and patient characteristics.In this monocentric, cross-sectional, epidemiological study, point prevalence was assessed at six time points in three gastroenterology/hepatology units within a German university hospital. Delirium was assessed using the 4 'As' Test (4AT) and delirium subtype by the delirium motor subtype scale. Patient characteristics were collected from patient charts.The sample consisted of 188 patients, aged 18 to 98 years (mean age 64, n=110 male). Of them, 18.1% of patients showed delirium symptoms (61.8% hypoactive, 29.4% mixed, and 8.8% hyperactive). For the participants aged ≥65 years (n=96), prevalence of delirium amounted to 26.0%. Significant associations were observed between delirium and the following characteristics: age (p=0.001), length of hospital stay until assessment (p=0.043), cerebrovascular disease (p=0.002), dementia (p=0.010), diabetes mellitus with chronic complications (p=0.012), and gender (nonsignificant trend, p=0.050), while no association was detected between moderate or severe liver disease and delirium (p=0.414).In conclusion, overall prevalence rates of delirium were rather low and did not increase in patients with liver disease.
在急性护理环境中，谵妄的患病率高达 22.0%。相比之下，30-40%的肝硬化患者可能会发展为肝性脑病，根据最近的病理生理学发现，这种情况已被归类为谵妄综合征。然而，在胃肠病学和肝病学领域，谵妄的患病率尚不清楚。
（i）确定胃肠病学/肝病学病房住院患者的谵妄患病率；（ii）分析谵妄的运动亚型；（iii）评估谵妄与患者特征之间的关联。
在这项单中心、横断面、流行病学研究中，在德国一所大学医院的三个胃肠病学/肝病学单元中，在六个时间点评估了时点患病率。使用 4 'As' 测试（4AT）评估谵妄，使用谵妄运动亚型量表评估谵妄亚型。从患者病历中收集患者特征。
样本包括 188 名年龄在 18 至 98 岁（平均年龄 64 岁，n=110 名男性）的患者。其中，18.1%的患者出现谵妄症状（61.8%为低活动型，29.4%为混合型，8.8%为高活动型）。对于年龄≥65 岁的参与者（n=96），谵妄的患病率为 26.0%。在以下特征与谵妄之间观察到显著关联：年龄（p=0.001）、评估前的住院时间（p=0.043）、脑血管疾病（p=0.002）、痴呆（p=0.010）、伴有慢性并发症的糖尿病（p=0.012）和性别（无显著趋势，p=0.050），而中度或重度肝病与谵妄之间无关联（p=0.414）。
总之，总体而言，谵妄的患病率相当低，并且在肝病患者中并未增加。
