Vuylsteke Peter, Bertrand Celine, Verhoef Gregor E G, Vandenberghe Peter
Hematology Unit, Department of Internal Medicine & Center of Human Genetics, University Hospital Leuven, 49 Herestraat, 3000 Leuven, Belgium.
Ann Hematol. 2004 Jul;83(7):487-8. doi: 10.1007/s00277-003-0839-2. Epub 2004 Jan 17.
A 61-year-old eutrophic male was diagnosed with vitamin B12 deficiency and megaloblastic anemia. A modified Schilling test suggested intestinal malabsorption unrelated to intrinsic factor deficiency. Subsequent colonoscopy revealed the presence of a Taenia tapeworm. The anemia resolved within days under therapy with niclosamide and temporary vitamin B12 supplements. The present case suggests that, in addition to other well-known parasitic agents, e.g., Diphyllobothrium latum and Giardia lamblia, Taenia infestation can also be a cause of intestinal vitamin B12 malabsorption.
一名61岁的营养良好男性被诊断为维生素B12缺乏和巨幼细胞贫血。改良的希林试验提示存在与内因子缺乏无关的肠道吸收不良。随后的结肠镜检查发现有绦虫。在接受氯硝柳胺治疗和临时补充维生素B12后,贫血在数天内得到缓解。本病例提示,除了其他知名的寄生虫病原体,如阔节裂头绦虫和蓝氏贾第鞭毛虫外,绦虫感染也可能是肠道维生素B12吸收不良的一个原因。