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持续性非卧床腹膜透析作为儿童终末期肾衰竭主要治疗方法的疗效

Efficacy of CAPD as the primary treatment for end-stage renal failure in children.

作者信息

Barakat M, Savage J M, Burns A, Stewart M

机构信息

Department of Child Health, Queen's University of Belfast, UK.

出版信息

Child Nephrol Urol. 1992;12(4):216-20.

PMID:1473095
Abstract

In the 6 years before this paper, all children presenting with end-stage renal failure (ESRF) in Northern Ireland were electively commenced on continuous ambulatory peritoneal dialysis (CAPD). In that period, 22 patients were treated, 16 received renal transplants and 6 remained on CAPD. Active treatment was withdrawn in 1 child due to obliterative peritonitis. There were no deaths. One incident of peritonitis was documented per 11.6 patient treatment months. Recurring peritonitis lead to catheter replacement in 3 patients. Other problems encountered were catheter exit site infections, hernia formation and in one instance, hydrothorax. Peritonitis was more common in children under 2 years of age as was undernutrition, growth retardation and developmental delay. Home CAPD can be recommended as a viable first option treatment for childhood ESRF where suitable haemodialysis facilities are not easily accessible.

摘要

在撰写本文前的6年里,北爱尔兰所有出现终末期肾衰竭(ESRF)的儿童均被选择性地开始进行持续性非卧床腹膜透析(CAPD)。在此期间,共治疗了22例患者,其中16例接受了肾移植,6例继续接受CAPD治疗。1名儿童因闭塞性腹膜炎停止了积极治疗。无死亡病例。每11.6个患者治疗月记录到1次腹膜炎事件。复发性腹膜炎导致3例患者更换导管。遇到的其他问题包括导管出口部位感染、疝气形成,还有1例出现胸腔积液。腹膜炎在2岁以下儿童中更为常见,营养不良、生长发育迟缓及发育延迟也是如此。在难以获得合适血液透析设施的情况下,家庭CAPD可作为儿童ESRF可行的首选治疗方法。

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