Ghahramani N, Gorban-Brennan N, Kliger A S, Finkelstein F O
Shiraz University Medical School, Iran.
Adv Perit Dial. 1995;11:164-7.
Previous studies have shown the incidence of peritonitis to be generally lower for patients performing continuous cycling peritoneal dialysis (CCPD) than patients maintained on continuous ambulatory peritoneal dialysis (CAPD). Recent changes in CAPD techniques, particularly the introduction of the UltraBag system, have resulted in a marked decrease in peritonitis rates in CAPD patients. The purpose of the present study was to compare peritoneal dialysis-related infections in 73 patients treated with CCPD and 57 patients treated with CAPD using the UltraBag system for a 12-month period. Demographic data of the two groups were comparable. Peritonitis rates were significantly lower in the patients treated with CAPD on the UltraBag (one infection/23 patient-months) than in patients treated with CCPD (one infection/14.4 patient-months, p < 0.05). Exit-site infections were also significantly lower in patients treated with CAPD (one episode/35 patient-months) compared to patients treated with CCPD (one episode/11.5 patient-months, p < 0.05). The spectrum of organisms causing infection was similar in both groups of patients. The study suggests that peritonitis and exit-site infections are significantly less common in patients treated with CAPD with the UltraBag system than in patients treated with CCPD.
以往研究表明，进行持续循环腹膜透析（CCPD）的患者腹膜炎发生率通常低于接受持续非卧床腹膜透析（CAPD）的患者。CAPD技术的近期变化，尤其是UltraBag系统的引入，已使CAPD患者的腹膜炎发生率显著降低。本研究的目的是比较73例接受CCPD治疗的患者和57例使用UltraBag系统进行CAPD治疗的患者在12个月期间与腹膜透析相关的感染情况。两组的人口统计学数据具有可比性。使用UltraBag进行CAPD治疗的患者腹膜炎发生率（1次感染/23患者-月）显著低于接受CCPD治疗的患者（1次感染/14.4患者-月，p<0.05）。与接受CCPD治疗的患者（1次发作/11.5患者-月）相比，接受CAPD治疗的患者出口处感染也显著更低（1次发作/35患者-月，p<0.05）。两组患者引起感染的微生物谱相似。该研究表明，与接受CCPD治疗的患者相比，使用UltraBag系统进行CAPD治疗的患者腹膜炎和出口处感染明显较少见。
