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[膀胱移行细胞癌细胞核形态及DNA含量的形态计量学分级研究]

[A morphometric grading study on the nucleus shape and DNA-content of transitional cell carcinoma of urinary bladder].

作者信息

Xia T L

机构信息

Institute of Urology, Beijing Medical University.

出版信息

Zhonghua Bing Li Xue Za Zhi. 1992 Aug;21(4):202-5.

PMID:1473202
Abstract

Totally 30 cases of TCC of the urinary bladder were analyzed with IBAS-2000 image analysis system. The nuclear area, perimeter, ellipse factor, etc and nucleus DNA content were measured. The morphometric grading was performed with five correlative factors for classification. They are nucleus perimeter, nucleus ellipse factor, DNA SDE, probability of the cells in C6 zone DNA and probability of the cells in C8 zone DNA. The coincident rate between morphometric grading and WHO grading was 88.9% in G1, 66.7% in G2, and 83.3% in G3. The results indicate that morphometric analysis is a valuable tool in the objective grading of bladder carcinoma.

摘要

应用IBAS-2000图像分析系统对30例膀胱移行细胞癌进行分析,测量细胞核面积、周长、椭圆因子等及细胞核DNA含量。采用五个相关因素进行形态计量分级以分类,它们是核周长、核椭圆因子、DNA标准差、C6区细胞DNA概率和C8区细胞DNA概率。形态计量分级与WHO分级的符合率在G1为88.9%,G2为66.7%,G3为83.3%。结果表明,形态计量分析是膀胱癌客观分级的一种有价值的工具。

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