Pérez A J, Thode G, Trelles O
Genetics Department and Computer Architecture Department, University of Málaga, 29071 Málaga, Spain.
Bioinformatics. 2004 Jan 22;20(2):291-2. doi: 10.1093/bioinformatics/btg414.
AnaGram is a web service for protein function assignment based on identity detection of small significant fragments (protomotifs) that can act as modular pieces in peptide construction. The system is able to assign function by finding correlations between protomotifs and functional annotations contained in SWISS-PROT and Medline databases. In addition, function ontologies are used for hierarchical organization of the predicted functions. Extensive tests have been carried out to evaluate the accuracy and performance of the system.
AnaGram是一个基于对小的重要片段(原基序)进行同一性检测的蛋白质功能分配网络服务,这些小片段可作为肽构建中的模块化组件。该系统能够通过查找原基序与SWISS-PROT和Medline数据库中包含的功能注释之间的相关性来分配功能。此外,功能本体用于对预测功能进行层次组织。已经进行了广泛的测试以评估该系统的准确性和性能。