Quang Dang Ngoc, Hashimoto Toshihiro, Nukada Makiko, Yamamoto Isao, Tanaka Masami, Asakawa Yoshinori
Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima, Japan.
Planta Med. 2003 Nov;69(11):1063-6. doi: 10.1055/s-2003-45159.
Four p-terphenyl derivatives named curtisians I-L (1-4) were isolated from the MeOH extract of the fruit bodies of Paxillus curtisii. Their structures were elucidated by 2D NMR, MS, IR and UV spectroscopy and chemical reaction. The absolute configurations of curtisians were determined by GC-MS on a chiral column of the hydrolyzed products with authentic samples. Their antioxidative activities were also estimated by examination of the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging effect.
从柯蒂斯疣柄牛肝菌子实体的甲醇提取物中分离出四种对三联苯衍生物，命名为柯蒂斯菌素I-L（1-4）。通过二维核磁共振、质谱、红外光谱、紫外光谱和化学反应对其结构进行了阐明。通过气相色谱-质谱联用仪在手性柱上对水解产物与标准样品进行分析，确定了柯蒂斯菌素的绝对构型。还通过检测1,1-二苯基-2-苦基肼基（DPPH）自由基清除效果评估了它们的抗氧化活性。
