Wang Kai-Jin, Zhang Ying-Jun, Yang Chong-Ren
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, PR China.
J Ethnopharmacol. 2005 Jun 3;99(2):259-64. doi: 10.1016/j.jep.2005.02.029. Epub 2005 Apr 7.
Fagopyrum dibotrys (D. Don.) Hara. is an erect perennial Polygonaceous herb. In China, its rhizome was used as folk medicine for the treatment of lung diseases, dysentery and rheumatism. The crude aqueous acetone extract from the rhizomes of this plant exhibited high antioxidant activity (SC50 = 10.95 microg/mL) in 1,1-diphenyl-2-picryldydrazyl (DPPH) radical scavenging assay. Detailed chemical investigation on the extract led to the isolation of two new phenols (1 and 2), together with 14 known antioxidant phenolic compounds (3-16). Their structures were determined by detailed spectroscopic analysis. The two new compounds were characterized as 3-methyl-gossypetin 8-O-beta-D-glucopyranoside (1) and 1,3,6'-tri-p-coumaroyl-6-feruloyl sucrose (diboside A, 2). The radical scavenging activity of all the isolated compounds was also described.
金荞麦（Fagopyrum dibotrys (D. Don.) Hara.）是一种直立的多年生蓼科草本植物。在中国，其根茎作为民间药物用于治疗肺部疾病、痢疾和风湿病。该植物根茎的粗水丙酮提取物在1,1-二苯基-2-苦基肼（DPPH）自由基清除试验中表现出高抗氧化活性（SC50 = 10.95微克/毫升）。对该提取物进行详细的化学研究，分离出两种新的酚类化合物（1和2），以及14种已知的具有抗氧化作用的酚类化合物（3 - 16）。通过详细的光谱分析确定了它们的结构。这两种新化合物分别被鉴定为3-甲基棉黄素8-O-β-D-吡喃葡萄糖苷（1）和1,3,6'-三对香豆酰基-6-阿魏酰基蔗糖（二糖苷A，2）。还描述了所有分离化合物的自由基清除活性。
