Wilson S M, Pediani J D, Jenkinson D M, Elder H Y
Institute of Physiology, University of Glasgow, Scotland.
Experientia. 1992 Dec 1;48(11-12):1115-7. doi: 10.1007/BF01948001.
Potassium permeability was monitored in human sweat glands and rat submandibular glands. Acetylcholine increased permeability in both tissues and the responses consisted of transient, calcium-independent and sustained, calcium-dependent components. Amiloride, a drug which inhibits Na(+)-H+ countertransport, impaired the regulation of potassium permeability in sweat glands but not in the submandibular gland. It is suggested that the stimulus-permeability coupling process in the sweat gland may be sensitive to the lowering of internal pH.
对人体汗腺和大鼠颌下腺的钾通透性进行了监测。乙酰胆碱可增加两种组织的通透性，其反应包括短暂的、不依赖钙的成分和持续的、依赖钙的成分。氨氯地平是一种抑制Na(+)-H+逆向转运的药物，它损害了汗腺中钾通透性的调节，但对颌下腺没有影响。提示汗腺中的刺激-通透性偶联过程可能对内pH值的降低敏感。
