Brown Daniel B, Gilula Louis A, Sehgal Manu, Shimony Joshua S
Mallinckrodt Institute of Radiology, 510 S Kingshighway Blvd, Box 8131, St Louis, MO 63110, USA.
AJR Am J Roentgenol. 2004 Feb;182(2):319-22. doi: 10.2214/ajr.182.2.1820319.
Most fractures treated with percutaneous vertebroplasty are subacute and less than 1 year old. We report our experience treating chronic vertebral fractures with vertebroplasty.
Our database identified 41 patients with symptomatic fractures more than 1 year old. These patients were categorized into subgroups determined by fracture age: 12 months 1 day-24 months (n = 16) or more than 24 months 1 day (n = 25). Changes in pain and mobility for the study group were compared with those in 49 patients with fractures less than 1 year old.
Thirty-three (80%) of the 41 patients in the study group had improvement in pain-seven (17%) had complete and 26 (63%) had partial relief. Forty-five (92%) of the 49 control group patients had improvement in pain-24 (49%) had complete and 21 (43%) had partial relief. The number of patients achieving partial or complete relief of pain was not statistically different between groups (p > 0.05), although complete relief was significantly more frequent in the control group (p = 0.002). Twenty patients (49%) in the study group versus 34 patients (69%) in the control group had improved mobility after vertebroplasty (p = 0.047). Patients with fractures 12 months 1 day-24 months old had improvement in mobility similar to that in patients in the control group (p = 0.962). Fractures more than 24 months 1 day old were associated with significantly less improvement in mobility (p = 0.006).
Most patients with fractures more than 1 year old will experience clinical benefit from vertebroplasty. Complete relief of pain is more likely when less mature fractures are treated.
大多数接受经皮椎体成形术治疗的骨折为亚急性骨折,且骨折时间小于1年。我们报告了我们用椎体成形术治疗慢性椎体骨折的经验。
我们的数据库确定了41例有症状且骨折时间超过1年的患者。这些患者按骨折年龄分为亚组:12个月零1天至24个月(n = 16)或超过24个月零1天(n = 25)。将研究组的疼痛和活动度变化与49例骨折时间小于1年的患者进行比较。
研究组41例患者中有33例(80%)疼痛得到改善,其中7例(17%)完全缓解,26例(63%)部分缓解。对照组49例患者中有45例(92%)疼痛得到改善,其中24例(49%)完全缓解,21例(43%)部分缓解。两组间实现部分或完全疼痛缓解的患者数量无统计学差异(p>0.05),尽管对照组的完全缓解更为常见(p = 0.002)。研究组20例患者(49%)与对照组34例患者(69%)在椎体成形术后活动度得到改善(p = 0.047)。骨折时间为12个月零1天至24个月的患者活动度改善情况与对照组患者相似(p = 0.962)。骨折时间超过24个月零1天的患者活动度改善明显较少(p = 0.006)。
大多数骨折时间超过1年的患者将从椎体成形术中获得临床益处。治疗较不成熟的骨折时更有可能实现疼痛完全缓解。