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HLA typing is not predictive of proliferative diabetic retinopathy in patients with younger onset type 2 diabetes mellitus.

作者信息

Mimura T, Amano S, Kato S, Araie M, Funatsu H, Kitano S, Shimizu E, Noma H, Yoshino O, Hori S

出版信息

Br J Ophthalmol. 2004 Feb;88(2):303-5. doi: 10.1136/bjo.2003.023945.

DOI:10.1136/bjo.2003.023945
PMID:14736798
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1772013/
Abstract
摘要

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1
HLA typing is not predictive of proliferative diabetic retinopathy in patients with younger onset type 2 diabetes mellitus.对于发病年龄较轻的2型糖尿病患者，HLA分型不能预测增殖性糖尿病视网膜病变。
Br J Ophthalmol. 2004 Feb;88(2):303-5. doi: 10.1136/bjo.2003.023945.
2
Diabetic retinopathy and HLA antigens in type 2 diabetes mellitus.
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3
Relationship between human leukocyte antigen status and proliferative diabetic retinopathy in patients with younger-onset type 1 diabetes mellitus.年轻发病的1型糖尿病患者中人类白细胞抗原状态与增殖性糖尿病视网膜病变的关系
Am J Ophthalmol. 2003 Jun;135(6):844-8. doi: 10.1016/s0002-9394(02)02291-2.
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Glutamic acid decarboxylase autoantibody prevalence and association with HLA genotype in patients with younger-onset type 1 diabetes and proliferative diabetic retinopathy.谷氨酸脱羧酶自身抗体在早发型1型糖尿病合并增殖性糖尿病视网膜病变患者中的患病率及其与HLA基因型的关联。
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The - 429 T/C and - 374 T/A gene polymorphisms of the receptor of advanced glycation end products gene are not risk factors for diabetic retinopathy in Caucasians with type 2 diabetes.晚期糖基化终末产物受体基因的 - 429 T/C和 - 374 T/A基因多态性并非2型糖尿病白种人发生糖尿病视网膜病变的危险因素。
Klin Monbl Augenheilkd. 2003 Dec;220(12):873-6. doi: 10.1055/s-2003-812553.
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Promoter polymorphism at the tumour necrosis factor/lymphotoxin-alpha locus is associated with type of diabetes but not with susceptibility to sight-threatening diabetic retinopathy.肿瘤坏死因子/淋巴毒素-α基因座的启动子多态性与糖尿病类型相关，但与威胁视力的糖尿病视网膜病变易感性无关。
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Genome-wide association study for sight-threatening diabetic retinopathy reveals association with genetic variation near the GRB2 gene.威胁视力的糖尿病视网膜病变的全基因组关联研究揭示了与GRB2基因附近遗传变异的关联。
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Association between the ICAM-1 K469E polymorphism and diabetic retinopathy in Type 2 diabetes mellitus: a meta-analysis.ICAM-1基因K469E多态性与2型糖尿病视网膜病变的关联：一项荟萃分析
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PAI-1 4G/5G insertion/deletion promoter polymorphism and microvascular complications in type 2 diabetes mellitus.纤溶酶原激活物抑制剂-1基因4G/5G插入/缺失启动子多态性与2型糖尿病微血管并发症
Wien Klin Wochenschr. 2005 Oct;117(19-20):707-10. doi: 10.1007/s00508-005-0425-9.

引用本文的文献

1
[Human leukocyte antigen (HLA) system in ophthalmology].[眼科中的人类白细胞抗原（HLA）系统]
Ophthalmologe. 2013 Sep;110(9):849-61. doi: 10.1007/s00347-013-2861-7.
2
HLA genes, islet autoantibodies and residual C-peptide at the clinical onset of type 1 diabetes mellitus and the risk of retinopathy 15 years later.HLA 基因、胰岛自身抗体和 15 年后糖尿病视网膜病变发生时的 1 型糖尿病临床发病时的 C 肽残留。
PLoS One. 2011 Mar 11;6(3):e17569. doi: 10.1371/journal.pone.0017569.

本文引用的文献

1
Relationship between human leukocyte antigen status and proliferative diabetic retinopathy in patients with younger-onset type 1 diabetes mellitus.年轻发病的1型糖尿病患者中人类白细胞抗原状态与增殖性糖尿病视网膜病变的关系
Am J Ophthalmol. 2003 Jun;135(6):844-8. doi: 10.1016/s0002-9394(02)02291-2.
2
Genetic heterogeneity of autoimmune diabetes: age of presentation in adults is influenced by HLA DRB1 and DQB1 genotypes (UKPDS 43). UK Prospective Diabetes Study (UKPDS) Group.自身免疫性糖尿病的遗传异质性：成人发病年龄受HLA DRB1和DQB1基因型影响（英国前瞻性糖尿病研究43）。英国前瞻性糖尿病研究（UKPDS）小组。
Diabetologia. 1999 May;42(5):608-16. doi: 10.1007/s001250051202.
3
HLA-DQB1*0201/0302 is associated with severe retinopathy in patients with IDDM.
Diabetologia. 1996 Nov;39(11):1313-7. doi: 10.1007/s001250050575.
4
HLA-associated susceptibility to type 2 (non-insulin-dependent) diabetes mellitus: the Wadena City Health Study.HLA与2型（非胰岛素依赖型）糖尿病易感性：瓦迪纳市健康研究
Diabetologia. 1993 Mar;36(3):234-8. doi: 10.1007/BF00399956.
5
[Risk factors for occurrence and progression of diabetic retinopathy].
Nippon Ganka Gakkai Zasshi. 1993 Aug;97(8):939-46.
6
Genetic susceptibility to non-insulin dependent diabetes mellitus and glucose intolerance are located in HLA region.非胰岛素依赖型糖尿病和葡萄糖耐量异常的遗传易感性位于人类白细胞抗原（HLA）区域。
BMJ. 1993 Jul 17;307(6897):155-9. doi: 10.1136/bmj.307.6897.155.
7
HL-A antigens and diabetes mellitus.组织相容性白细胞抗原与糖尿病
Lancet. 1974 Oct 12;2(7885):864-6. doi: 10.1016/s0140-6736(74)91201-x.
8
Diabetes mellitus. Report of a WHO Study Group.糖尿病。世界卫生组织研究小组报告。
World Health Organ Tech Rep Ser. 1985;727:1-113.
9
[Macrophages and HLA-DR expression in proliferative vitreoretinopathy].[增殖性玻璃体视网膜病变中的巨噬细胞与人类白细胞抗原-DR表达]
Fortschr Ophthalmol. 1990;87(4):340-3.
10
Genetic marker associations with proliferative retinopathy in persons diagnosed with diabetes before 30 yr of age.30岁之前被诊断为糖尿病的人群中基因标记与增殖性视网膜病变的关联。
Diabetes. 1992 Jul;41(7):879-85. doi: 10.2337/diab.41.7.879.