Sun Hongyan, Cong Xianling, Sun Ran, Wang Chuanwen, Wang Xue, Liu Ya
Tissue Bank, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China; Nutrition and Food Hygiene department, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China.
Tissue Bank, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China.
Diabetes Res Clin Pract. 2014 May;104(2):e46-9. doi: 10.1016/j.diabres.2014.01.028. Epub 2014 Feb 10.
A meta-analysis was conducted to evaluate the association of ICAM-1 K469E gene polymorphism with diabetic retinopathy susceptibility in Type 2 diabetes mellitus. Seven studies involving 1094 cases and 909 controls were included. Current studies suggest that K469E polymorphism in ICAM-1 gene might not affect individual susceptibility to DR.
进行了一项荟萃分析，以评估ICAM-1 K469E基因多态性与2型糖尿病患者糖尿病视网膜病变易感性之间的关联。纳入了7项研究，共1094例病例和909例对照。目前的研究表明，ICAM-1基因中的K469E多态性可能不会影响个体对糖尿病视网膜病变的易感性。
