• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

生物活性肽通过碳纳米管跨细胞膜转运

Translocation of bioactive peptides across cell membranes by carbon nanotubes.

作者信息

Pantarotto Davide, Briand Jean-Paul, Prato Maurizio, Bianco Alberto

机构信息

Institut de Biologie Moléculaire et Cellulaire, UPR9021 CNRS, Strasbourg, France.

出版信息

Chem Commun (Camb). 2004 Jan 7(1):16-7. doi: 10.1039/b311254c. Epub 2003 Nov 3.

DOI:10.1039/b311254c
PMID:14737310
Abstract

Functionalised carbon nanotubes are able to cross the cell membrane and to accumulate in the cytoplasm or reach the nucleus without being toxic for the cell up to 10 [micro sign]M.

摘要

功能化碳纳米管能够穿过细胞膜，在细胞质中积累或进入细胞核，在浓度高达10微摩尔时对细胞无毒。

相似文献

1
Translocation of bioactive peptides across cell membranes by carbon nanotubes.生物活性肽通过碳纳米管跨细胞膜转运
Chem Commun (Camb). 2004 Jan 7(1):16-7. doi: 10.1039/b311254c. Epub 2003 Nov 3.
2
Direct imaging of single-walled carbon nanotubes in cells.细胞中单壁碳纳米管的直接成像。
Nat Nanotechnol. 2007 Nov;2(11):713-7. doi: 10.1038/nnano.2007.347. Epub 2007 Oct 28.
3
Nanotube molecular transporters: internalization of carbon nanotube-protein conjugates into Mammalian cells.纳米管分子转运体：碳纳米管-蛋白质偶联物内化进入哺乳动物细胞
J Am Chem Soc. 2004 Jun 9;126(22):6850-1. doi: 10.1021/ja0486059.
4
Influence of acid functionalization on the cardiopulmonary toxicity of carbon nanotubes and carbon black particles in mice.酸功能化对小鼠体内碳纳米管和炭黑颗粒心肺毒性的影响。
Toxicol Appl Pharmacol. 2009 Sep 15;239(3):224-32. doi: 10.1016/j.taap.2009.05.019. Epub 2009 May 27.
5
[Construction and functional study of a cell penetrating peptide-based expression vector for targeted delivery of proteins into the cell nuclei].基于细胞穿透肽的蛋白质靶向细胞核递送表达载体的构建及功能研究
Nan Fang Yi Ke Da Xue Xue Bao. 2006 Oct;26(10):1394-9, 1407.
6
Cell-penetrating cis-gamma-amino-l-proline-derived peptides.细胞穿透性顺式γ-氨基-L-脯氨酸衍生肽
J Am Chem Soc. 2005 Jul 6;127(26):9459-68. doi: 10.1021/ja051648k.
7
Direct visualization by confocal fluorescent microscopy of the permeation of myristoylated peptides through the cell membrane.通过共聚焦荧光显微镜直接观察肉豆蔻酰化肽透过细胞膜的过程。
IUBMB Life. 2002 Jul;54(1):33-6. doi: 10.1080/15216540213823.
8
Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes.化学功能化碳纳米管穿过质膜的转位机制。
Biomaterials. 2012 Apr;33(11):3334-43. doi: 10.1016/j.biomaterials.2012.01.024. Epub 2012 Jan 30.
9
Carbon nanotubes as a protein toxin transporter for selective HER2-positive breast cancer cell destruction.碳纳米管作为一种蛋白质毒素转运体用于选择性破坏HER2阳性乳腺癌细胞。
Mol Biosyst. 2009 Oct;5(10):1224-31. doi: 10.1039/b906948h. Epub 2009 Jul 7.
10
Translocation of an Aib-containing peptide through cell membranes.含Aib的肽通过细胞膜的转运。
Bioorg Med Chem Lett. 2008 Jul 15;18(14):3999-4001. doi: 10.1016/j.bmcl.2008.06.005. Epub 2008 Jun 6.

引用本文的文献

1
Carbon-Nanotube-Based Nanocomposites in Environmental Remediation: An Overview of Typologies and Applications and an Analysis of Their Paradoxical Double-Sided Effects.基于碳纳米管的纳米复合材料在环境修复中的应用：类型与应用概述及其矛盾的双面效应分析
J Xenobiot. 2025 May 21;15(3):76. doi: 10.3390/jox15030076.
2
Antimicrobial Nanotubes: From Synthesis and Promising Antimicrobial Upshots to Unanticipated Toxicities, Strategies to Limit Them, and Regulatory Issues.抗菌纳米管：从合成、有前景的抗菌效果到意外毒性、限制毒性的策略及监管问题
Nanomaterials (Basel). 2025 Apr 21;15(8):633. doi: 10.3390/nano15080633.
3
A DFTB study on the electronic response of encapsulated DNA nucleobases onto chiral CNTs as a sequencer.
基于密度泛函理论的含能 DNA 碱基对手性 CNT 电子响应研究作为一种测序仪。
Sci Rep. 2024 May 11;14(1):10826. doi: 10.1038/s41598-024-61677-0.
4
Nanotechnology in the Diagnosis and Treatment of Antibiotic-Resistant Infections.纳米技术在抗生素耐药性感染的诊断与治疗中的应用
Antibiotics (Basel). 2024 Jan 25;13(2):121. doi: 10.3390/antibiotics13020121.
5
Delivered complementation in planta (DCIP) enables measurement of peptide-mediated protein delivery efficiency in plants.体内递补（DCIP）可用于测量植物中肽介导的蛋白质递药效率。
Commun Biol. 2023 Aug 12;6(1):840. doi: 10.1038/s42003-023-05191-5.
6
Coarse-grained modeling of polystyrene-modified CNTs and their interactions with lipid bilayers.粗粒化建模聚苯乙烯修饰的碳纳米管及其与脂双层的相互作用。
Biophys J. 2023 May 16;122(10):1748-1761. doi: 10.1016/j.bpj.2023.04.005. Epub 2023 Apr 13.
7
Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes.使用磁控碳纳米管进行化学抵抗性脑胶质瘤的机械纳米手术。
Sci Adv. 2023 Mar 29;9(13):eade5321. doi: 10.1126/sciadv.ade5321.
8
Sensing and Stimulation Applications of Carbon Nanomaterials in Implantable Brain-Computer Interface.碳纳米材料在植入式脑-机接口中的传感和刺激应用
Int J Mol Sci. 2023 Mar 8;24(6):5182. doi: 10.3390/ijms24065182.
9
Stimuli-Responsive Boron-Based Materials in Drug Delivery.刺激响应型硼基药物递送材料
Int J Mol Sci. 2023 Feb 1;24(3):2757. doi: 10.3390/ijms24032757.
10
Functionalized Carbon Nanoparticles as Theranostic Agents and Their Future Clinical Utility in Oncology.功能化碳纳米颗粒作为诊疗试剂及其在肿瘤学中的未来临床应用
Bioengineering (Basel). 2023 Jan 12;10(1):108. doi: 10.3390/bioengineering10010108.